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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
MGI:894689
23 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ywhaetm1Awb/Ywhae+
involves: 129S6/SvEvTac 		abnormal heart left ventricle morphology J:192860
decreased litter size J:192860
thin ventricle myocardium compact layer J:192860
ventricular septal defect J:192860
Ywhaetm1Awb/Ywhaetm1Awb
either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * NIH Black Swiss) 		abnormal brain morphology J:84075
abnormal cerebral cortex morphology J:84075
abnormal hippocampus pyramidal cell layer J:84075
decreased neuronal migration J:84075
perinatal lethality, incomplete penetrance J:84075
Ywhaetm1Awb/Ywhaetm1Awb
involves: 129S6/SvEvTac 		abnormal cell cycle J:192860
abnormal fetal cardiomyocyte physiology J:192860
abnormal heart morphology J:192860
abnormal heart ventricle morphology J:192860
abnormal myocardial trabeculae morphology J:192860
cyanosis J:192860
decreased fetal cardiomyocyte proliferation J:192860
decreased mitotic index J:192860
dilated heart ventricle J:192860
perinatal lethality, complete penetrance J:192860
thin myocardium compact layer J:192860
thin ventricle myocardium compact layer J:192860
thin ventricular wall J:192860
ventricular septal defect J:192860
Ywhaetm2.1Awb/Ywhaetm2.1Awb
Tg(Zp3-cre)93Knw/0
involves: C57BL/6J 		normal reproductive system phenotype J:281426
Ywhaetm2.2Awb/Ywhaetm2.2Awb
involves: C57BL/6N * FVB 		female infertility J:281426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory