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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Numbl
numb-like
MGI:894702
35 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Emx1tm1(cre)Krj/Emx1+
Numbtm1Ynj/Numbtm1Ynj
Numbltm1Wmz/Numbltm1Wmz
involves: 129S2/SvPas * 129X1/SvJ * CD-1 		abnormal brain ventricle morphology J:87149
abnormal cerebral cortex morphology J:87149
abnormal cortical marginal zone morphology J:87149
abnormal embryonic neuroepithelium morphology J:87149
abnormal forebrain morphology J:87149
abnormal hearing physiology J:87149
abnormal hippocampus morphology J:87149
abnormal lateral ventricle morphology J:87149
abnormal neuron differentiation J:87149
abnormal neuron specification J:87149
absent corpus callosum J:87149
circling J:87149
decreased body size J:87149
ectopic cortical neuron J:87149
enlarged brain ventricles J:87149
female infertility J:87149
increased neuron apoptosis J:87149
male infertility J:87149
postnatal lethality, incomplete penetrance J:87149
small thalamus J:87149
social withdrawal J:87149
sporadic seizures J:87149
stereotypic behavior J:87149
Numbtm1Ynj/Numbtm1Ynj
Numbltm1Wmz/Numbltm1Wmz
Tg(Nes-cre)1Wmz/0
involves: 129X1/SvJ 		abnormal embryonic neuroepithelium morphology J:79917
abnormal neural tube morphology J:79917
decreased embryo size J:79917
decreased embryonic neuroepithelium thickness J:79917
decreased neuronal precursor cell number J:79917
embryonic lethality during organogenesis, complete penetrance J:79917
Numbtm1Ynj/Numbtm1Ynj
Numbltm1Wmz/Numbltm1Wmz
Tg(Nes-cre/Esr1*)4Ynj/0
involves: 129X1/SvJ * C57BL/6 		abnormal ependyma morphology J:127227
abnormal lateral ventricle morphology J:127227
abnormal olfactory bulb morphology J:127227
abnormal postnatal subventricular zone morphology J:127227
abnormal rostral migratory stream morphology J:127227
enlarged lateral ventricles J:127227
increased neuron apoptosis J:127227
postnatal growth retardation J:127227
Numbtm1Zili/Numbtm1Zili
Numbltm1Zili/Numbltm1Zili
Tg(Mx1-cre)1Cgn/?
involves: 129/Sv * C57BL/6 * CBA 		normal hematopoietic system phenotype J:133550
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory