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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ldb1
LIM domain binding 1
MGI:894762
56 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ldb1tm1.1Gsv/Ldb1tm1.1Gsv
involves: 129P2/OlaHsd * C57BL/6 * FVB 		abnormal embryonic erythropoiesis J:196469
abnormal vascular development J:196469
abnormal visceral yolk sac morphology J:196469
Ldb1tm1Lmgd/Ldb1+
involves: C3H/He * C57BL/6 		no abnormal phenotype detected J:98485
Ldb1tm1Lmgd/Ldb1tm1Lmgd
involves: CD-1 		abnormal allantois morphology J:81152
abnormal craniofacial morphology J:81152
abnormal extraembryonic tissue morphology J:81152
abnormal foregut morphology J:81152
abnormal heart morphology J:81152
abnormal hematopoietic system morphology/development J:81152
abnormal neural plate morphology J:81152
abnormal primitive streak formation J:81152
abnormal primitive streak morphology J:81152
abnormal primordial germ cell morphology J:81152
abnormal rhombomere 3 morphology J:81152
abnormal rhombomere 5 morphology J:81152
abnormal visceral yolk sac morphology J:81152
absent allantois J:81152
absent heart J:81152
absent midbrain-hindbrain boundary J:81152
absent visceral yolk sac blood islands J:81152
decreased embryo size J:81152
embryonic growth arrest J:81152
embryonic lethality, complete penetrance J:81152
embryonic-extraembryonic boundary constriction J:81152
failure of chorioallantoic fusion J:81152
fused somites J:81152
increased somite number J:81152
kinked neural tube J:81152
rostral body truncation J:81152
rostral-caudal axis duplication J:81152
split notochord J:81152
Ldb1tm1Lmgd/Ldb1tm2Lmgd
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: C57BL/6J * CBA/J 		abnormal diastema morphology J:208345
abnormal palatal mesenchymal cell proliferation J:208345
abnormal palatal shelf elevation J:208345
abnormal palatal shelf morphology J:208345
abnormal tongue position J:208345
arrest of tooth development J:208345
cleft secondary palate J:208345
normal craniofacial phenotype J:208345
decreased molar number J:208345
decreased palatal shelf size J:208345
neonatal lethality, complete penetrance J:208345
Ldb1tm1Witz/Ldb1tm1Witz
Tg(NPHS2-cre)295Lbh/0
involves: C57BL/6 * SJL 		abnormal glomerular capillary endothelium morphology J:122505
abnormal podocyte foot process morphology J:122505
abnormal renal glomerulus basement membrane morphology J:122505
absent glomerular endothelium fenestra J:122505
albuminuria J:122505
dilated renal tubule J:122505
podocyte foot process effacement J:122505
premature death J:122505
renal cast J:122505
renal glomerular synechia J:122505
renal glomerulus atrophy J:122505
Ldb1tm2Lmgd/Ldb1tm2Lmgd
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * FVB/N * SJL 		absent cerebellar foliation J:123471
decreased Purkinje cell number J:123471
small cerebellum J:123471
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory