Mylk Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mylk
myosin, light polypeptide kinase
MGI:894806

27 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mylk^tm1.1Bph/Mylk^tm1.1Bph involves: C57BL/6N	no abnormal phenotype detected	J:204964
Mylk^tm1.1Bph/Mylk^tm1.1Bph Tg(Myh11-cre,-EGFP)2Mik/0 involves: C57BL/6 * C57BL/6N * DBA/2	abnormal small intestine morphology	J:204964
	normal growth/size/body region phenotype	J:204964
	impaired smooth muscle contractility	J:204964
	neonatal lethality, incomplete penetrance	J:204964
	prenatal lethality, incomplete penetrance	J:204964
Mylk^tm1.1Bph/Mylk^tm1.2Bph Tg(Myh11-cre,-EGFP)2Mik/0 involves: C57BL/6 * C57BL/6N * DBA/2	abnormal small intestine morphology	J:204964
	normal growth/size/body region phenotype	J:204964
	impaired smooth muscle contractility	J:204964
	neonatal lethality, incomplete penetrance	J:204964
	prenatal lethality, incomplete penetrance	J:204964
Mylk^tm1Avs/Mylk^tm1Avs B6.129-Mylk^tm1Avs	abnormal muscle contractility	J:106058
Mylk^tm1Avs/Mylk^tm1Avs B6.129-Mylk^tm1Avs	abnormal muscle relaxation	J:106058
Mylk^tm1Dmw/Mylk^tm1Dmw involves: C57BL/6	decreased susceptibility to injury	J:83394
Mylk^tm1Mzhu/Mylk^tm1Mzhu involves: 129S6/SvEvTac	no abnormal phenotype detected	J:141907
Mylk^tm1Mzhu/Mylk^tm1Mzhu Tagln^{tm1(cre/ERT2)Feil}/? involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	abnormal defecation	J:141907
	abnormal digestive system physiology	J:141907
	abnormal gastrointestinal motility	J:141907
	abnormal intestinal peristalsis	J:141907
	abnormal intestinal smooth muscle morphology	J:141907
	abnormal intestine morphology	J:141907
	abnormal urinary bladder physiology	J:141907
	abnormal vertebral column morphology	J:141907
	decreased food intake	J:141907
	decreased systemic arterial blood pressure	J:141907
	decreased systemic arterial diastolic blood pressure	J:141907
	decreased systemic arterial systolic blood pressure	J:141907
	distended abdomen	J:141907
	distended ileum	J:141907
	distended jejunum	J:141907
	ischuria	J:141907
	premature death	J:141907
	small intestinal inflammation	J:141907

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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