Dbx1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dbx1
developing brain homeobox 1
MGI:94867

18 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dbx1^tm1Tmj/Dbx1^tm1Tmj involves: 129P2/OlaHsd * C57BL/6	abnormal medulla oblongata morphology	J:165285
	abnormal pre-Botzinger complex morphology	J:165285
	abnormal pre-Botzinger complex physiology	J:165285
	cyanosis	J:165285
	neonatal lethality, complete penetrance	J:165285
	respiratory failure	J:165285
Dbx1^tm1Tmj/Dbx1^tm1Tmj involves: 129P2/OlaHsd * C57BL/6J	abnormal GABAergic neuron morphology	J:70191
	abnormal somatic nervous system physiology	J:89813
	abnormal ventral interneuron 0 morphology	J:70191, J:89813
	neonatal lethality, complete penetrance	J:70191
Dbx1^tm2Jcor/Dbx1^tm1Tmj Tg(Nkx2-1-cre)2Sand/0 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal action potential	J:221571
	abnormal hypothalamus secretion	J:221571
	abnormal response to novel odor	J:221571
	decreased body weight	J:221571
	decreased compensatory feeding amount	J:221571
	decreased food intake	J:221571
	decreased percent body fat/body weight	J:221571
	increased locomotor activity	J:221571
Dbx1^tm2Jcor/Dbx1^tm2Jcor involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:221571

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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