Dcn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dcn
decorin
MGI:94872

34 phenotypes from 3 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dcn^tm1.2Geno/Dcn^tm1.2Geno B6.129S2(Cg)-Dcn^tm1.2Geno	no abnormal phenotype detected	J:223791
Dcn^tm1.2Geno/Dcn^tm1.2Geno B6.129S2(Cg)-Dcn^tm1.2Geno	normal vision/eye phenotype	J:223791
Dcn^tm1Ioz/Dcn⁺ either: C.Cg-Dcn^tm1Ioz or C3.Cg-Dcn^tm1Ioz	decreased susceptibility to bacterial infection	J:68640
Dcn^tm1Ioz/Dcn^tm1Ioz C.129(Cg)-Dcn^tm1Ioz	abnormal humoral immune response	J:92428
Dcn^tm1Ioz/Dcn^tm1Ioz either: C.Cg-Dcn^tm1Ioz or C3.Cg-Dcn^tm1Ioz	decreased susceptibility to bacterial infection	J:68640
Dcn^tm1Ioz/Dcn^tm1Ioz involves: 129/Sv * Black Swiss * C57BL/6	abnormal stomach mucosa morphology	J:53511
	normal neoplasm	J:53511
	salivary gland epithelial hyperplasia	J:53511
Dcn^tm1Ioz/Dcn^tm1Ioz involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	abnormal bone structure	J:91512
	abnormal cutaneous collagen fibril morphology	J:91512
	abnormal tendon morphology	J:91512
	decreased skin tensile strength	J:91512
	thin dermal layer	J:91512
Dcn^tm1Ioz/Dcn^tm1Ioz involves: 129S1/Sv * 129X1/SvJ	reduced female fertility	J:180914
Dcn^tm1Ioz/Dcn^tm1Ioz involves: 129S1/Sv * 129X1/SvJ * Black Swiss	abnormal cutaneous collagen fibril morphology	J:39212
	abnormal periodontal ligament morphology	J:66512
	abnormal renal tubule epithelium morphology	J:75298
	abnormal tendon morphology	J:39212
	normal behavior/neurological phenotype	J:39212
	decreased skin tensile strength	J:39212
	dilated renal tubule	J:75298
	normal hematopoietic system phenotype	J:39212
	normal homeostasis/metabolism phenotype	J:39212
	hydronephrosis	J:75298
	normal immune system phenotype	J:39212
	increased glomerular capsule space	J:91499
	increased renal tubule apoptosis	J:75298
	kidney atrophy	J:75298
	loose skin	J:39212
	periodontal ligament hypercellularity	J:66512
	renal interstitial fibrosis	J:75298
	renal tubule atrophy	J:75298
	normal skeleton phenotype	J:39212
	thin dermal layer	J:39212
	thin skin	J:39212
	tubular nephritis	J:75298
	normal vision/eye phenotype	J:39212
Tg(CAG-cat,-Dcn*)#Debi/0 Tg(Kera-cre)KC4.3Wwk/0 involves: FVB/N	abnormal cornea posterior stroma morphology	J:177392
	abnormal cornea stroma morphology	J:177392
	cornea opacity	J:177392

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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