Ddc Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ddc
dopa decarboxylase
MGI:94876

51 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ddc^{em1(IMPC)Hmgu}/Ddc⁺ C57BL/6N-Ddc^{em1(IMPC)Hmgu}/Ieg	abnormal tooth morphology	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	increased mean corpuscular volume	J:211773
Ddc^{em1(IMPC)Hmgu}/Ddc^{em1(IMPC)Hmgu} C57BL/6N-Ddc^{em1(IMPC)Hmgu}/Ieg	preweaning lethality, complete penetrance	J:211773
Ddc^{Gt(OST129277)Lex}/Ddc^{Gt(OST129277)Lex} involves: 129S5/SvEvBrd * C57BL/6J	preweaning lethality, complete penetrance	J:103485
Ddc^tm1.1Nwlh/Ddc^tm1.1Nwlh involves: C57BL/6	abnormal dopamine level	J:197646
	abnormal locomotor activation	J:197646
	abnormal maternal nurturing	J:197646
	abnormal motor learning	J:197646
	abnormal noradrenaline level	J:197646
	abnormal synaptic neurotransmitter level	J:197646
	akinesia	J:197646
	blepharoptosis	J:197646
	decreased body size	J:197646
	decreased dopamine level	J:197646
	decreased heart rate	J:197646
	decreased locomotor activity	J:197646
	decreased serotonin level	J:197646
	decreased systemic arterial systolic blood pressure	J:197646
	delayed eyelid opening	J:197646
	impaired coordination	J:197646
	increased anxiety-related response	J:197646
	increased thigmotaxis	J:197646
	increased vertical activity	J:197646
	induced hyperactivity	J:197646
	jerky movement	J:197646
	limb grasping	J:197646
	postnatal growth retardation	J:197646
	prenatal lethality, incomplete penetrance	J:197646
	tremors	J:197646
Ddc^tm1.1Rhrs/Ddc^tm1.1Rhrs Tg(Ggt1-cre)M3Egn/0 129.Cg-Ddc^tm1.1Rhrs Tg(Ggt1-cre)M3Egn	abnormal kidney physiology	J:175630
	abnormal response/metabolism to endogenous compounds	J:175630
	albuminuria	J:175630
	decreased circulating aldosterone level	J:175630
	decreased dopamine level	J:175630
	decreased renin activity	J:175630
	increased circulating creatinine level	J:175630
	increased heart weight	J:175630
	increased kidney weight	J:175630
	increased mean systemic arterial blood pressure	J:175630
	increased renin activity	J:175630
	increased systemic arterial systolic blood pressure	J:175630
	oxidative stress	J:175630
	premature death	J:175630
	salt-sensitive hypertension	J:175630
	tubulointerstitial nephritis	J:175630
Ddc^tm1.1Rhrs/Ddc^tm1.1Rhrs Tg(Ggt1-cre)M3Egn/0 involves: 129 * C57BL/6 * SJL	abnormal kidney physiology	J:175630
	abnormal response/metabolism to endogenous compounds	J:175630
	albuminuria	J:175630
	decreased circulating aldosterone level	J:175630
	decreased dopamine level	J:175630
	decreased renin activity	J:175630
	increased circulating creatinine level	J:175630
	increased heart weight	J:175630
	increased kidney weight	J:175630
	increased mean systemic arterial blood pressure	J:175630
	increased renin activity	J:175630
	increased systemic arterial systolic blood pressure	J:175630
	oxidative stress	J:175630
	premature death	J:175630
	salt-sensitive hypertension	J:175630
	tubulointerstitial nephritis	J:175630
Ddc^tm1Umon/Ddc^tm1Umon B6.129S(FVB)-Ddc^tm1Umon	embryonic lethality, complete penetrance	J:250494
Ddc^tm1Umon/Ddc^tm1Umon FVB.129S(B6)-Ddc^tm1Umon	embryonic lethality, complete penetrance	J:250494
Ddc^tm1Umon/Ddc^tm1Umon involves: 129S/SvEv * C57BL/6 * FVB/N	abnormal embryo development	J:250494
	abnormal embryonic tissue morphology	J:250494
	abnormal maternal nurturing	J:250494
	decreased dopamine level	J:250494
	decreased embryo size	J:250494
	decreased serotonin level	J:250494
	impaired adaptive thermogenesis	J:250494
	impaired coordination	J:250494
	lethality throughout fetal growth and development, incomplete penetrance	J:250494
	reduced female fertility	J:250494

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