Dio1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dio1
deiodinase, iodothyronine, type I
MGI:94896

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dio1^{em1(IMPC)Hmgu}/Dio1^{em1(IMPC)Hmgu} C57BL/6N-Dio1^{em1(IMPC)Hmgu}/Ieg	abnormal kidney morphology	J:211773
Dio1^tm1Vag/Dio1^tm1Vag involves: 129 * C57BL/6	abnormal feces composition	J:104508
	abnormal response/metabolism to endogenous compounds	J:104508
	abnormal thyroid gland physiology	J:104508
	abnormal thyroid hormone level	J:104508
	abnormal urine homeostasis	J:104508
	decreased circulating cholesterol level	J:104508
	increased body weight	J:104508
	increased circulating thyroxine level	J:104508
	increased circulating triiodothyronine level	J:104508
	increased thyroxine level	J:104508
	increased triiodothyronine level	J:104508

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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