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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dlk1
delta like non-canonical Notch ligand 1
MGI:94900
55 phenotypes from 5 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dlk1em1(IMPC)Wtsi/Dlk1em1(IMPC)Wtsi
C57BL/6N-Dlk1em1(IMPC)Wtsi/WtsiIeg 		decreased circulating glucose level J:211773
decreased lean body mass J:211773
increased mean corpuscular hemoglobin J:211773
increased total body fat amount J:211773
preweaning lethality, incomplete penetrance J:211773
Dlk1tm1.1Jvs/Dlk1+
Myf5tm3(cre)Sor/Myf5+
involves: 129P2/SvPas * 129S4/SvJaeSor * C57BL/6 * FVB/N 		abnormal cell differentiation J:167124
decreased body weight J:167124
decreased brown adipose tissue mass J:167124
decreased cell proliferation J:167124
decreased skeletal muscle fiber number J:167124
impaired skeletal muscle regeneration J:167124
increased inflammatory response J:167124
increased skeletal muscle fiber diameter J:167124
increased skeletal muscle fiber size J:167124
maternal imprinting J:167124
skeletal muscle fibrosis J:167124
Dlk1tm1.1Jvs/Dlk1+
Tg(Tek-cre)12Flv/0
involves: 129P2/OlaHsd * C3H * C57BL/6 * FVB/N 		normal growth/size/body region phenotype J:194130
normal mortality/aging J:194130
Dlk1tm1.1Jvs/Dlk1+
Tg(Ins2-cre)25Mgn/0
involves: 129P2/OlaHsd * C57BL/6 * DBA * FVB/N 		normal growth/size/body region phenotype J:194130
normal mortality/aging J:194130
Dlk1tm1.1Jvs/Dlk1+
Tg(Gh1-cre)bKnmn/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		normal growth/size/body region phenotype J:194130
normal mortality/aging J:194130
Dlk1tm1.2Jvs/Dlk1+
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal placenta labyrinth morphology J:194130
abnormal placental labyrinth vasculature morphology J:194130
decreased body size J:194130
decreased body weight J:194130
decreased fat cell size J:194130
decreased trophoblast glycogen cell number J:194130
normal growth/size/body region phenotype J:194130
normal mortality/aging J:194130
neonatal lethality J:194130
placental labyrinth hypoplasia J:194130
postnatal growth retardation J:194130
postnatal lethality J:194130
Dlk1tm1.2Jvs/Dlk1tm1.2Jvs
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal survival J:194130
decreased body weight J:194130
maternal imprinting J:194130
Dlk1tm1Hsul/Dlk1+
involves: 129 * C57BL/6J 		abnormal fat pad morphology J:77909
maternal imprinting J:77909
postnatal growth retardation J:77909
Dlk1tm1Hsul/Dlk1tm1Hsul
either: (involves: 129 * BALB/c) or (involves: 129 * C57BL/6J) 		abnormal fat pad morphology J:77909
asymmetric rib joints J:77909
decreased litter size J:77909
enlarged liver J:77909
fetal growth retardation J:77909
hepatic steatosis J:77909
hyperlipidemia J:77909
increased circulating cholesterol level J:77909
increased fat cell size J:77909
narrow eye opening J:77909
neonatal lethality, incomplete penetrance J:77909
postnatal growth retardation J:77909
rib fusion J:77909
Dlk1tm1Srba/Dlk1+
involves: 129X1/SvJ * C57BL/6 		maternal imprinting J:145076
Dlk1tm1Srba/Dlk1tm1Srba
involves: 129X1/SvJ * C57BL/6 		abnormal B cell number J:145076
abnormal spleen B cell follicle morphology J:145076
abnormal spleen marginal zone morphology J:145076
decreased body size J:145076
decreased immature B cell number J:145076
decreased mature B cell number J:145076
increased IgG1 level J:145076
increased IgG2a level J:145076
increased IgG2b level J:145076
increased IgG2c level J:145076
increased IgG3 level J:145076
increased IgM level J:145076
increased immature B cell number J:145076
increased immunoglobulin level J:145076
increased marginal zone B cell number J:145076
increased transitional stage B cell number J:145076
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory