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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dlx3
distal-less homeobox 3
MGI:94903
30 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dlx3em1(IMPC)Mbp/Dlx3+
C57BL/6N-Dlx3em1(IMPC)Mbp/MbpMmucd 		abnormal heart morphology J:211773
edema J:211773
embryonic growth retardation J:211773
hemorrhage J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating calcium level J:211773
increased freezing behavior J:211773
small heart J:211773
Dlx3em1(IMPC)Mbp/Dlx3em1(IMPC)Mbp
C57BL/6N-Dlx3em1(IMPC)Mbp/MbpMmucd 		preweaning lethality, complete penetrance J:211773
Dlx3tm1Mso/Dlx3tm1Mso
involves: 129S1/Sv * 129X1/SvJ * CF-1 		abnormal pericardium morphology J:52247
abnormal placenta development J:52247
abnormal placenta labyrinth morphology J:52247
abnormal placental labyrinth vasculature morphology J:52247
abnormal spongiotrophoblast layer morphology J:52247
absent placental labyrinth J:52247
embryonic growth arrest J:52247
embryonic lethality during organogenesis, complete penetrance J:52247
Dlx3tm2Mso/Dlx3tm2Mso
Not Specified 		embryonic lethality during organogenesis, complete penetrance J:140203
Dlx3tm2Mso/Dlx3tm3Mso
Tg(KRT14-cre)#Smr/0
involves: C57BL/6J * SJL/J 		abnormal epidermal layer morphology J:140203
abnormal hair follicle development J:140203
abnormal hair follicle morphology J:140203
abnormal hair shaft morphology J:140203
abnormal postnatal growth J:140203
accelerated hair follicle regression J:140203
alopecia J:140203
enlarged sebaceous gland J:140203
epidermal hyperplasia J:140203
increased hair follicle cell proliferation J:140203
thick dermal layer J:140203
thick epidermis J:140203
weight loss J:140203
Dlx3tm3Mso/Dlx3tm3Mso
Tg(KRT14-cre)#Smr/0
involves: C57BL/6J * SJL/J 		abnormal postnatal growth J:140203
alopecia J:140203
epidermal hyperplasia J:140203
weight loss J:140203
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory