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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dmp1
dentin matrix protein 1
MGI:94910
68 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dmp1tm1.1(KOMP)Vlcg/Dmp1tm1.1(KOMP)Vlcg
C57BL/6N-Dmp1tm1.1(KOMP)Vlcg/Ucd 		abnormal bone structure J:211773
abnormal kidney morphology J:211773
decreased blood urea nitrogen level J:211773
decreased body length J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased circulating phosphate level J:211773
decreased grip strength J:211773
decreased heart rate J:211773
enlarged kidney J:211773
increased circulating alkaline phosphatase level J:211773
increased lean body mass J:211773
increased total body fat amount J:211773
prolonged RR interval J:211773
Dmp1tm1.1Mis/Dmp1tm1.1Mis
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * CBA 		abnormal compact bone morphology J:135314
abnormal long bone metaphysis morphology J:135314
delayed bone ossification J:135314
short femur J:135314
Dmp1tm1Mis/Dmp1tm1.1Mis
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * CBA 		abnormal compact bone morphology J:135314
abnormal long bone metaphysis morphology J:135314
delayed bone ossification J:135314
Dmp1tm1Mis/Dmp1tm1Mis
involves: 129S7/SvEvBrd 		abnormal compact bone morphology J:135314
abnormal long bone metaphysis morphology J:135314
delayed bone ossification J:135314
short femur J:135314
Dmp1tm1Mis/Dmp1tm1Mis
involves: 129S7/SvEvBrd * C57BL/6 		abnormal acellular cementum morphology J:241769
abnormal alveolar process morphology J:89498, J:241769
abnormal bone mineralization involved in bone maturation J:241769
abnormal cellular cementum morphology J:241769
abnormal cementoblast morphology J:241769
abnormal cementocyte canaliculus morphology J:241769
abnormal cementocyte dendritic process morphology J:241769
abnormal cementocyte lacuna morphology J:241769
abnormal cementocyte lacunocanalicular system morphology J:241769
abnormal cementum mineralization J:241769
abnormal dental pulp cavity morphology J:89498
abnormal dentin development J:89498
abnormal dentin mineralization J:89498
abnormal dentin morphology J:89498, J:241769
abnormal long bone hypertrophic chondrocyte zone J:85859
abnormal osteocyte canaliculus morphology J:241769
abnormal osteocyte lacuna morphology J:241769
abnormal osteocyte lacunocanalicular system morphology J:241769
abnormal periodontal ligament morphology J:241769
abnormal periodontium morphology J:241769
abnormal predentin morphology J:89498
abnormal tooth mineralization J:89498
alveolar process atrophy J:241769
decreased bone mineralization J:241769
decreased cementoblast number J:241769
decreased molar number J:89498
growth retardation of molars J:89498
increased diameter of long bones J:85859
increased osteoblast cell number J:241769
increased osteoid volume J:241769
increased susceptibility to bacterial infection J:241769
misaligned teeth J:241769
reduced enamel thickness J:89498
normal skeleton phenotype J:85859
Dmp1tm1Mis/Dmp1tm1Mis
involves: 129S7/SvEvBrd * CD-1 		abnormal bone marrow development J:184352
abnormal bone remodeling J:184352
abnormal circulating protein level J:115339
abnormal compact bone morphology J:184352
abnormal kidney physiology J:115339
abnormal long bone metaphysis morphology J:184352
abnormal osteocyte lacuna morphology J:115339
abnormal osteocyte lacunocanalicular system morphology J:115339
abnormal osteocyte morphology J:115339
abnormal skeleton development J:115339
abnormal vascular development J:184352
arrested osteoblast differentiation J:184352
decreased circulating calcium level J:115339
decreased circulating phosphate level J:115339, J:184352
decreased osteoclast cell number J:184352
delayed bone ossification J:184352
increased alkaline phosphatase activity J:184352
increased bone trabecula number J:184352
increased circulating parathyroid hormone level J:115339
osteomalacia J:115339
rachitic rosary J:115339
rickets J:115339
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory