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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dpp4
dipeptidylpeptidase 4
MGI:94919
20 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dpp4em1Rba/Dpp4+
C57BL/6J-Dpp4em1Rba 		decreased susceptibility to Coronaviridae infection induced morbidity/mortality J:279834
normal homeostasis/metabolism phenotype J:279834
increased susceptibility to Coronaviridae infection J:279834
increased susceptibility to pulmonary hyaline membrane formation J:279834
increased susceptibility to weight loss J:279834
lung hemorrhage J:279834
lung inflammation J:279834
pulmonary alveolar edema J:279834
respiratory distress J:279834
Dpp4em1Rba/Dpp4em1Rba
C57BL/6J-Dpp4em1Rba 		decreased lymphocyte cell number J:279723
normal homeostasis/metabolism phenotype J:279834
increased monocyte cell number J:279723
increased neutrophil cell number J:279723
increased susceptibility to Coronaviridae infection J:279723, J:279834
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:279834
increased susceptibility to pulmonary hyaline membrane formation J:279834
increased susceptibility to weight loss J:279834
lung hemorrhage J:279834
lung inflammation J:279834
pulmonary alveolar edema J:279834
respiratory distress J:279834
Dpp4em3Gpt/Dpp4em3Gpt
C57BL/6JGpt-Dpp4em3Gpt 		normal immune system phenotype J:324112
Dpp4tm1b(EUCOMM)Wtsi/Dpp4tm1b(EUCOMM)Wtsi
C57BL/6N-Dpp4tm1b(EUCOMM)Wtsi/Ics 		abnormal auditory brainstem response J:211773
decreased lymphocyte cell number J:211773
improved glucose tolerance J:211773
Dpp4tm1Lex/Dpp4tm1Lex
involves: 129S/SvEvBrd * C57BL/6J 		improved glucose tolerance J:195941
Dpp4tm1Nwa/Dpp4tm1Nwa
C57BL/6-Dpp4tm1Nwa 		decreased body weight J:62709
improved glucose tolerance J:62709
increased circulating glucagon level J:62709
increased circulating insulin level J:62709
increased insulin secretion J:62709
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory