Drd2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Drd2
dopamine receptor D2
MGI:94924

40 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Adora2a^tm1Jfc/Adora2a^tm1Jfc Drd2^tm1Low/Drd2^tm1Low involves: 129 * C57BL/6	abnormal locomotor activation	J:102700
Cm/+ Drd2^tm1Low/Drd2^tm1Low involves: 101/H * 129S2/SvPas * C3H/HeH * C3H/HeSn * C57BL/6J	normal behavior/neurological phenotype	J:156905
	decreased dopamine level	J:156905
	decreased locomotor activity	J:156905
	normal nervous system phenotype	J:156905
Drd1^tm1Jcd/Drd1⁺ Drd2^tm1Ebo/Drd2^tm1Ebo involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	normal mortality/aging	J:91781
Drd1^tm1Jcd/Drd1^tm1Jcd Drd2^tm1Ebo/Drd2⁺ involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	abnormal duodenum morphology	J:91781
	abnormal eating behavior	J:91781
	abnormal stomach morphology	J:91781
	gastrointestinal hemorrhage	J:91781
	intestinal ulcer	J:91781
	postnatal growth retardation	J:91781
	premature death	J:91781
	small intestinal inflammation	J:91781
Drd1^tm1Jcd/Drd1^tm1Jcd Drd2^tm1Ebo/Drd2^tm1Ebo involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	abnormal digestive system development	J:91781
	abnormal digestive system physiology	J:91781
	abnormal hypothalamus physiology	J:91781
	abnormal intestinal smooth muscle morphology	J:91781
	abnormal intestine morphology	J:91781
	absent gastric milk in neonates	J:91781
	aphagia	J:91781
	decreased body size	J:91781
	decreased locomotor activity	J:91781
	gastrointestinal hemorrhage	J:91781
	normal nervous system phenotype	J:91781
	postnatal growth retardation	J:91781
	postnatal lethality, complete penetrance	J:91781
Drd2^{tm1(IL2RA)Koba}/Drd2⁺ B6.129P2-Drd2^{tm1(IL2RA)Koba}	abnormal locomotor activation	J:85929
	decreased dopaminergic neuron number	J:85929
	unidirectional circling	J:85929
Drd2^tm1Ebo/Drd2^tm1Ebo Drd3^tm1Dac/Drd3^tm1Dac involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	abnormal behavior	J:96229
	abnormal defecation	J:96229
	abnormal emotion/affect behavior	J:96229
	decreased locomotor activity	J:96229
	decreased vertical activity	J:96229
Drd2^tm1Low/Drd2^tm1Low Tg(GFAP-CRYAB)141.6Mes/0 involves: 129S2/SvPas * C57BL/6 * FVB/N	normal nervous system phenotype	J:194407
Drd2^tm1Schm/Drd2⁺ Drd3^tm1Schm/Drd3^tm1Schm involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal locomotor behavior	J:79483
Drd2^tm1Schm/Drd2^tm1Schm Drd3^tm1Schm/Drd3⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal dopamine level	J:79483
	abnormal locomotor behavior	J:79483
Drd2^tm1Schm/Drd2^tm1Schm Drd3^tm1Schm/Drd3^tm1Schm B6.Cg-Drd2^tm1Schm Drd3^tm1Schm	abnormal intestinal absorption	J:106280
	abnormal intestinal transit time	J:106280
	abnormal large intestinal transit time	J:106280
	decreased body weight	J:106280
	increased defecation amount	J:106280
	increased fluid intake	J:106280
	increased food intake	J:106280
Drd2^tm1Schm/Drd2^tm1Schm Drd3^tm1Schm/Drd3^tm1Schm involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal dopamine level	J:79483
	abnormal locomotor behavior	J:79483
	decreased body weight	J:79483
	hunched posture	J:79483
	postnatal lethality, incomplete penetrance	J:79483

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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