Drd5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Drd5
dopamine receptor D5
MGI:94927

14 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Drd5^tm1.1Stl/Drd5^tm1.1Stl involves: C57BL/6	no abnormal phenotype detected	J:211355
Drd5^tm1.1Stl/Drd5^tm1.1Stl Tg(Pomc-cre)1Lowl/0 involves: C57BL/6 * FVB/N	normal behavior/neurological phenotype	J:211355
Drd5^tm1.2Stl/Drd5^tm1.2Stl involves: C57BL/6	preweaning lethality, complete penetrance	J:211355
Drd5^tm1Dgen/Drd5^tm1Dgen B6.129P2-Drd5^tm1Dgen/J	normal vision/eye phenotype	J:185955
Drd5^tm1Dgen/Drd5^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:101679
Drd5^tm1Shay/Drd5^tm1Shay B6.129P2-Drd5^tm1Shay	normal behavior/neurological phenotype	J:209099
	enhanced behavioral response to methamphetamine	J:209099
	normal nervous system phenotype	J:209099
Drd5^tm1Sib/Drd5^tm1Sib B6.129S4-Drd5^tm1Sib	abnormal kidney physiology	J:95570
	increased systemic arterial blood pressure	J:95570
	increased systemic arterial diastolic blood pressure	J:95570
	increased systemic arterial systolic blood pressure	J:95570
Drd5^tm1Sib/Drd5^tm1Sib involves: 129S4/SvJae * C57BL/6	abnormal adrenal gland physiology	J:95908
	abnormal kidney physiology	J:95570
	abnormal sympathetic nervous system physiology	J:95908
	hypertension	J:95908
	increased heart weight	J:95908
	increased systemic arterial blood pressure	J:95570, J:95908
	increased systemic arterial diastolic blood pressure	J:95570, J:95908
	increased systemic arterial systolic blood pressure	J:95570, J:95908

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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