About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ebf1
early B cell factor 1
MGI:95275
70 phenotypes from 9 alleles in 13 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ebf1em1(IMPC)Mbp/Ebf1+
C57BL/6N-Ebf1em1(IMPC)Mbp/MbpMmucd 		abnormal liver morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
decreased prepulse inhibition J:211773
enlarged heart J:211773
enlarged kidney J:211773
enlarged lymph nodes J:211773
increased circulating serum albumin level J:211773
no spontaneous movement J:211773
Ebf1em1(IMPC)Mbp/Ebf1em1(IMPC)Mbp
C57BL/6N-Ebf1em1(IMPC)Mbp/MbpMmucd 		abnormal placenta morphology J:211773
no spontaneous movement J:211773
preweaning lethality, incomplete penetrance J:211773
Ebf1m1Btlr/Ebf1m1Btlr
C57BL/6J-Ebf1m1Btlr 		decreased B cell number J:265157
decreased IgD level J:265157
increased CD4-positive, alpha-beta T cell number J:265157
increased single-positive T cell number J:265157
increased T cell number J:265157
Ebf1m2Btlr/Ebf1m2Btlr
C57BL/6J-Ebf1m2Btlr 		abnormal humoral immune response J:265158
decreased B cell number J:265158
decreased B-1 B cell number J:265158
decreased B-2 B cell number J:265158
decreased IgD level J:265158
decreased IgM level J:265158
increased B-1a cell number J:265158
increased B-1b cell number J:265158
increased CD4-positive, alpha-beta T cell number J:265158
increased IgM level J:265158
increased single-positive T cell number J:265158
increased T cell number J:265158
increased tumor necrosis factor secretion J:265158
Ebf1M3Btlr/Ebf1M3Btlr
C57BL/6J-Ebf1M3Btlr 		decreased B-1 B cell number J:265160
increased CD4-positive, alpha-beta T cell number J:265160
increased single-positive T cell number J:265160
increased T cell number J:265160
Ebf1M4Btlr/Ebf1M4Btlr
C57BL/6J-Ebf1M4Btlr 		decreased B cell number J:267560
decreased NK cell number J:267560
increased alpha-beta T cell number J:267560
increased CD4-positive, alpha-beta T cell number J:267560
increased CD8-positive, alpha-beta T cell number J:267560
Ebf1M5Btlr/Ebf1M5Btlr
C57BL/6J-Ebf1M5Btlr 		abnormal lymphocyte morphology J:272841
decreased B cell number J:272841
decreased B-1 B cell number J:272841
Ebf1m6Btlr/Ebf1m6Btlr
C57BL/6J-Ebf1m6Btlr 		abnormal lymphocyte morphology J:272842
decreased B cell number J:272842
decreased B-1 B cell number J:272842
decreased effector memory CD4-positive, alpha-beta T cell number J:272842
decreased IgD level J:272842
increased alpha-beta T cell number J:272842
increased CD4-positive, alpha-beta T cell number J:272842
increased CD8-positive, alpha-beta T cell number J:272842
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * C57BL/6 * SJL 		decreased B-1 B cell number J:182210
decreased marginal zone B cell number J:182210
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 * SJL 		arrested B cell differentiation J:182210
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Ighg1tm1(cre)Cgn/Ighg1+
involves: 129P2/OlaHsd * C57BL/6 * SJL 		decreased germinal center B cell number J:182210
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Polr2atm1(cre/ERT2)Bbd/Polr2a+
involves: C57BL/6 * SJL 		abnormal germinal center B cell physiology J:182210
arrested B cell differentiation J:182210
decreased B cell proliferation J:182210
decreased germinal center B cell number J:182210
decreased IgG1 level J:182210
decreased IgG3 level J:182210
decreased immature B cell number J:182210
decreased marginal zone B cell number J:182210
decreased pre-B cell number J:182210
decreased spleen germinal center number J:182210
decreased transitional stage B cell number J:182210
normal immune system phenotype J:182210
increased B cell apoptosis J:182210
increased B cell number J:182210
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Tg(Cr2-cre)3Cgn/0
involves: C57BL/6 * SJL 		decreased B-1 B cell number J:182210
decreased marginal zone B cell number J:182210
Ebf1tm1Rug/Ebf1tm1Rug
involves: 129S2/SvPas 		abnormal B cell morphology J:52607
absent B-1 B cells J:52607
absent mature B cells J:52607
arrested B cell differentiation J:52607
decreased body size J:52607
decreased IgM level J:52607
decreased pro-B cell number J:52607
normal hematopoietic system phenotype J:52607
premature death J:52607
Ebf1tm1Rug/Ebf1tm1Rug
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal bone marrow morphology J:147179
abnormal bone ossification J:147179
abnormal bone structure J:147179
abnormal long bone epiphyseal plate morphology J:147179
abnormal trabecular bone morphology J:147179
decreased body size J:147179
decreased bone marrow cell number J:147179
decreased bone mineralization J:147179
decreased subcutaneous adipose tissue amount J:147179
delayed bone mineralization J:147179
hepatic steatosis J:147179
increased osteoblast cell number J:147179
increased osteoclast cell number J:147179
increased trabecular bone thickness J:147179
premature death J:147179
Ebf1tm1Rug/Ebf1tm1Rug
involves: 129S2/SvPas * C57BL/6 		abnormal anterior commissure pars posterior morphology J:44591
abnormal brain internal capsule morphology J:44591
abnormal lateral ganglionic eminence morphology J:44591
abnormal metencephalon morphology J:65601
abnormal striatum morphology J:44591
abnormal ventral striatum morphology J:44591
decreased striatum size J:44591
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory