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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Eif4e
eukaryotic translation initiation factor 4E
MGI:95305
15 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Eif4eGt(RRO036)Byg/Eif4e+
Krastm3Tyj/Kras+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N 		decreased lung tumor incidence J:224214
decreased tumor growth/size J:224214
increased cellular sensitivity to oxidative stress J:224214
oxidative stress J:224214
Eif4etm1.1Lfur/Eif4etm1.1Lfur
Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 		decreased tumor incidence J:163589
Fmr1tm1Cgr/Y
Tg(ACTB-Eif4e)#Ppp/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal brain morphology J:227667
abnormal contextual conditioning behavior J:227667
abnormal response to novel object J:227667
abnormal social investigation J:227667
abnormal spatial learning J:227667
hyperactivity J:227667
increased anxiety-related response J:227667
increased stereotypic behavior J:227667
Tg(ACTB-Eif4e)#Ppp/0
Tg(IghMyc)22Bri/0
involves: C57BL * SJL 		decreased B cell apoptosis J:89878
increased lymphoma incidence J:89878
Tg(IghMyc)22Bri/0
Tg(Lck/Emu-Eif4e)#Ppp/0
involves: C57BL * SJL 		increased lymphoma incidence J:89878
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory