About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Eln
elastin
MGI:95317
31 phenotypes from 1 allele in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Elntm1Dyl/Eln+
B6.129-Elntm1Dyl 		abnormal artery morphology J:86535
abnormal blood vessel physiology J:86535
abnormal cardiovascular system physiology J:86535
artery stenosis J:86535
cardiac hypertrophy J:86535
decreased aorta elastin content J:86535
decreased aorta wall thickness J:86535
hypertension J:86535
increased cardiac output J:86535
increased cardiac stroke volume J:86535
increased circulating renin level J:86535
increased mean systemic arterial blood pressure J:86535
increased systemic arterial diastolic blood pressure J:86535
increased systemic arterial systolic blood pressure J:86535
Elntm1Dyl/Eln+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal aortic valve annulus morphology J:184494
abnormal aortic valve morphology J:184494
abnormal cardiovascular system physiology J:184494
Elntm1Dyl/Eln+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal aorta elastic tissue morphology J:51109
abnormal blood vessel elastic tissue morphology J:51109
abnormal blood vessel physiology J:51109
abnormal vascular smooth muscle morphology J:51109
decreased aorta elastin content J:51109
Elntm1Dyl/Eln+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal blood vessel elastic tissue morphology J:96831
abnormal blood vessel physiology J:96831
abnormal vascular wound healing J:96831
Elntm1Dyl/Elntm1Dyl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal aorta wall morphology J:47771
abnormal artery development J:47771
abnormal artery morphology J:47771
abnormal lung development J:110736
abnormal pulmonary artery morphology J:47771
abnormal subclavian artery morphology J:47771
abnormal vascular smooth muscle morphology J:47771
artery stenosis J:47771
atelectasis J:110736
emphysema J:110736
impaired lung alveolus development J:110736
increased aorta wall thickness J:47771
overexpanded pulmonary alveolus J:110736
postnatal lethality, complete penetrance J:47771, J:110736
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory