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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Emx1
empty spiracles homeobox 1
MGI:95387
260 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Adcy1tm1Ito/Adcy1tm1.1Ito
Emx1tm1(cre)Ito/Emx1+
B6.129P2-Emx1tm1(cre)Ito Adcy1tm1Ito Adcy1tm1.1Ito 		abnormal barrel cortex morphology J:137123
decreased miniature excitatory postsynaptic current amplitude J:137123
normal nervous system phenotype J:137123
reduced long-term potentiation J:137123
Adcy3tm2.1Drs/Adcy3tm2.1Drs
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129X1/SvJ 		abnormal depression-related behavior J:281839
abnormal long-term spatial reference memory J:281839
abnormal object recognition memory J:281839
abnormal response to new environment J:281839
behavioral despair J:281839
hypoactivity J:281839
impaired spatial learning J:281839
Afdntm1c(EUCOMM)Hmgu/Afdntm1c(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J * C57BL/6N 		abnormal cell cycle J:215584
abnormal cerebral cortex morphology J:215584
abnormal cortical ventricular zone morphology J:215584
abnormal embryonic neuroepithelium morphology J:215584
abnormal hippocampus morphology J:215584
abnormal neocortex morphology J:215584
abnormal nervous system tract morphology J:215584
abnormal radial glial cell morphology J:215584
abnormal stratification in cerebral cortex J:215584
abnormal telencephalon development J:215584
ectopic neuron J:215584
increased brain size J:215584
increased neocortex size J:215584
increased neuronal precursor cell number J:215584
increased radial glial cell number J:215584
thin cortical plate J:215584
Arhgef9tm1Betz/Y
Emx1tm1(cre)Yql/Emx1+
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		abnormal neuron morphology J:141850
Atrtm2Bal/Atrtm2Bal
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J 		abnormal cerebral cortex morphology J:181920
abnormal corpus callosum morphology J:181920
abnormal stratification in cerebral cortex J:181920
hippocampus hypoplasia J:181920
Atxn1tm2Hzo/Atxn1tm2Hzo
Atxn1ltm2Hzo/Atxn1ltm2Hzo
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S7/SvEvBrd 		decreased anxiety-related response J:240674
decreased cerebral cortex cell number J:240674
decreased dentate gyrus size J:240674
impaired contextual conditioning behavior J:240674
increased locomotor activity J:240674
thin cerebral cortex J:240674
Bdnftm1Krj/Bdnf+
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J 		normal growth/size/body region phenotype J:84683
Bdnftm1Krj/Bdnftm1Lfr
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J 		abnormal cerebral cortex morphology J:96903
abnormal hippocampus morphology J:96903
abnormal medium spiny neuron morphology J:96903
abnormal nest building behavior J:84683
abnormal visual cortex morphology J:84683
decreased body weight J:84683
decreased striatum size J:96903
delayed eyelid opening J:84683
increased aggression J:84683
limb grasping J:96903
obese J:84683
premature death J:84683
reduced fertility J:84683
thin cerebral cortex J:84683
Bhlhe22tm2.1Meg/Bhlhe22tm2.1Meg
Emx1tm1(cre)Krj/Emx1+
involves: 129/Sv * 129S2/SvPas 		normal behavior/neurological phenotype J:158273
normal integument phenotype J:158273
Bhlhe22tm2.1Meg/Bhlhe22tm2.1Meg
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J 		abnormal anterior corticospinal tract morphology J:182304
absent corpus callosum J:182304
absent hippocampal commissure J:182304
Bicd2tm1Hgrd/Bicd2tm1Hgrd
Emx1tm1(cre)Krj/Emx1+
involves: C57BL/6 		abnormal hippocampus layer morphology J:210236
abnormal neuronal migration J:210236
abnormal stratification in cerebral cortex J:210236
normal nervous system phenotype J:210236
Bptftm1.1Cwu/Bptftm1.1Cwu
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 		abnormal cerebral cortex morphology J:334252
abnormal head shape J:334252
abnormal neuron specification J:334252
abnormal neuronal precursor proliferation J:334252
abnormal stratification in cerebral cortex J:334252
normal behavior/neurological phenotype J:334252
decreased body weight J:334252
decreased brain weight J:334252
decreased forebrain size J:334252
decreased neuronal precursor cell number J:334252
forebrain hypoplasia J:334252
increased neuron apoptosis J:334252
microgliosis J:334252
normal mortality/aging J:334252
Brpf1tm1c(EUCOMM)Wtsi/Brpf1tm1c(EUCOMM)Wtsi
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J * C57BL/6N 		abnormal behavior J:241490
abnormal cell cycle checkpoint function J:224155
abnormal cell physiology J:240552
abnormal corpus callosum morphology J:224155
abnormal dentate gyrus morphology J:224155
abnormal hippocampal mossy fiber morphology J:224155
abnormal hippocampus CA1 region morphology J:224155
abnormal hippocampus development J:224155
abnormal hippocampus morphology J:224155
abnormal hippocampus neuron morphology J:224155
abnormal hippocampus pyramidal cell layer J:224155
abnormal hippocampus region morphology J:224155
abnormal neocortex morphology J:224155, J:241490
abnormal nest building behavior J:241490
abnormal neuronal precursor cell migration J:224155
abnormal neuronal stem cell morphology J:224155
abnormal radial glial cell morphology J:224155
decreased body size J:241490
decreased corpus callosum size J:241490
decreased dentate gyrus size J:224155
decreased food intake J:241490
decreased neocortex size J:241490
decreased neuronal precursor cell number J:224155
decreased neuronal precursor proliferation J:224155, J:241490
decreased radial glial cell number J:224155
increased subiculum size J:224155
limb grasping J:241490
normal nervous system phenotype J:241490
postnatal lethality, incomplete penetrance J:224155, J:241490
prenatal growth retardation J:241490
prenatal lethality, incomplete penetrance J:241490
thin cortical plate J:241490
Btbd9tm1c(EUCOMM)Wtsi/Btbd9tm1c(EUCOMM)Wtsi
Emx1tm1(cre)Yql/Emx1+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6N 		abnormal primary motor cortex morphology J:282582
abnormal primary somatosensory cortex morphology J:282582
abnormal sleep behavior J:282582
hyperactivity J:282582
impaired coordination J:282582
increased thermal nociceptive threshold J:282582
Cadpstm1.1Tfr/Cadpstm1.2Tfr
Emx1tm1(cre)Ito/Emx1+
B6.Cg-Emx1tm1(cre)Ito Cadpstm1.1Tfr Cadpstm1.2Tfr 		abnormal dentate gyrus morphology J:204664
abnormal Golgi trans cisterna morphology J:204664
abnormal hippocampus pyramidal cell morphology J:204664
abnormal synaptic bouton morphology J:204664
normal nervous system phenotype J:204664
Camk2atm1.1Yelg/Camk2atm1.1Yelg
Emx1tm1.1(cre)Ito/0
B6J.Cg-Camk2atm1.1Yelg Emx1tm1.1(cre)Ito 		impaired contextual conditioning behavior J:216169
impaired spatial learning J:216169
Cdh2tm1Glr/Cdh2tm1Glr
Emx1tm1(cre)Krj/Emx1+
involves: 129S6/SvEvTac * C57BL/6 		abnormal cerebral cortex morphology J:215584
abnormal cortical ventricular zone morphology J:215584
abnormal neocortex morphology J:215584
abnormal nervous system tract morphology J:215584
abnormal radial glial cell morphology J:215584
ectopic neuron J:215584
increased neuronal precursor cell number J:215584
thickened cerebral cortex J:215584
Cdyltm1.1Yuw/Cdyltm1.1Yuw
Emx1tm1(cre)Yql/Emx1+
involves: 129S2/SvPas * C57BL/6 		abnormal neuronal migration J:251551
normal behavior/neurological phenotype J:251551
increased susceptibility to pharmacologically induced seizures J:251551
Celf4tm1.1Frk/Celf4tm1.1Frk
Emx1tm1(cre)Krj/?
involves: 129 * C57BL/6J 		increased susceptibility to induction of seizure by inducing agent J:19671
Celsr1tm1Fati/Celsr1tm1Fati
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ 		whorled hair J:157059
Celsr3tm1Agof/Celsr3tm2Agof
Emx1tm1(cre)Krj/Emx1+
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal anterior commissure morphology J:134879
abnormal brain internal capsule morphology J:134879
abnormal corticospinal tract morphology J:134879
Chn1tm1Ito/Chn1tm1.1Ito
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6NSlc 		normal behavior/neurological phenotype J:209606
Chrm1tm2.1Stl/Chrm1tm2.1Stl
Emx1tm1.1(cre)Ito/0
involves: 129P2/OlaHsd 		abnormal excitatory postsynaptic currents J:156540
abnormal long-term depression J:156540
abnormal miniature excitatory postsynaptic currents J:156540
decreased paired-pulse facilitation J:156540
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6 * C57BL/6N 		abnormal cerebral cortex morphology J:240674
abnormal pyramidal neuron dendrite morphology J:240674
decreased anxiety-related response J:240674
decreased cerebral cortex cell number J:240674
decreased dentate gyrus size J:240674
decreased neurotransmitter release J:240674
impaired contextual conditioning behavior J:240674
increased locomotor activity J:240674
thin cerebral cortex J:240674
Clcn7tm3.1Tjj/Clcn7tm3.1Tjj
Emx1tm1.1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 		abnormal cerebral cortex morphology J:155176
abnormal dentate gyrus morphology J:155176
abnormal hippocampus morphology J:155176
abnormal lysosome physiology J:155176
astrocytosis J:155176
enlarged lateral ventricles J:155176
normal growth/size/body region phenotype J:155176
hippocampal neuron degeneration J:155176
limb grasping J:155176
loss of cortex neurons J:155176
loss of hippocampal neurons J:155176
microgliosis J:155176
normal mortality/aging J:155176
neurodegeneration J:155176
normal skeleton phenotype J:155176
Cmtr1tm1b(EUCOMM)Hmgu/Cmtr1tm1b(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
Tg(Thy1-YFP)HJrs/0
involves: 129S2/SvPas * C57BL/6J * C57BL/6N * CBA 		abnormal dendrite morphology J:300305
abnormal susceptibility to Riboviria infection J:300305
decreased neocortex size J:300305
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Emx1tm1(cre)Yql/Emx1+
B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem 		abnormal cerebral cortex morphology J:92923
abnormal hippocampus morphology J:92923
abnormal nursing J:92923
absent corpus callosum J:92923
absent dentate gyrus J:92923
absent hippocampal commissure J:92923
absent hippocampus CA1 region J:92923
absent hippocampus CA2 region J:92923
absent hippocampus CA3 region J:92923
decreased body size J:92923
dilated lateral ventricle J:92923
increased susceptibility to pharmacologically induced seizures J:92923
male infertility J:92923
seizures J:92923
Dact1tm1.1Bnrc/Dact1tm1.2Bnrc
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas 		abnormal dendritic spine morphology J:159217
normal nervous system phenotype J:159217
Eif4a3tm1.1Dlsi/Eif4a3+
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J 		abnormal neocortex morphology J:235650
abnormal neuronal stem cell morphology J:235650
abnormal telencephalon development J:235650
absent telencephalon J:235650
decreased brain size J:235650
decreased forebrain size J:235650
decreased neocortex size J:235650
microcephaly J:235650
Emx1tm1(cre)Ito/Emx1+
Grin1tm1Stl/Grin1tm2Stl
involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6 		abnormal postnatal growth J:64064
abnormal primary somatosensory cortex morphology J:80900
abnormal somatosensory cortex morphology J:64064
absent barrels in primary somatosensory cortex J:64064, J:80900
decreased body weight J:64064
reduced NMDA receptor mediated synaptic activity in barrel cortex J:64064
Emx1tm1(cre)Ito/Emx1+
Hes1tm1Fgu/Hes1tm1Hojo
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal neurohypophysis morphology J:121843
abnormal pituitary diverticulum morphology J:121843
abnormal pituitary gland development J:121843
abnormal pituitary gland morphology J:121843
abnormal pituitary infundibular stalk morphology J:121843
absent pituitary intermediate lobe J:121843
increased somatotroph cell number J:121843
pituitary gland hypoplasia J:121843
Emx1tm1(cre)Ito/Emx1+
Olig2tm1Qrlu/Olig2tm1Qrlu
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal myelination J:105071
Emx1tm1(cre)Ito/Emx1+
Htr2atm1Grch/Htr2atm2Grch
129S6.Cg-Htr2atm1Grch Htr2atm2Grch Emx1tm1(cre)Ito 		normal behavior/neurological phenotype J:110958
Emx1tm1(cre)Ito/Emx1+
Rgs9tm1.1(cre)Yql/Rgs9+
Tg(HTT*97Q)IXwy/0
involves: 129P2/OlaHsd * FVB 		normal behavior/neurological phenotype J:208675
normal nervous system phenotype J:208675
Emx1tm1(cre)Ito/Emx1+
Tg(HTT*97Q)IXwy/0
involves: 129P2/OlaHsd * FVB 		normal behavior/neurological phenotype J:208675
decreased locomotor activity J:208675
impaired coordination J:208675
normal nervous system phenotype J:208675
Emx1tm1(cre)Ito/Emx1+
Hes1tm1Kag/Hes1tm1Kag
involves: 129P2/OlaHsd * C57BL/6 * CBA 		normal nervous system phenotype J:139170
Emx1tm1(cre)Ito/Emx1+
Hes1tm1Kag/Hes1tm1Kag
Hes3tm1Kag/Hes3tm1Kag
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal brain morphology J:139170
abnormal embryonic neuroepithelium morphology J:139170
abnormal neuron differentiation J:139170
absent choroid plexus J:139170
increased Cajal-Retzius cell number J:139170
Emx1tm1(cre)Ito/Emx1+
Rac1tm1Atai/Rac1tm1Jms
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * ICR 		abnormal barrel cortex morphology J:140575
abnormal brain commissure morphology J:140575
abnormal corpus callosum morphology J:140575
abnormal dentate gyrus morphology J:140575
abnormal hippocampus pyramidal cell layer J:140575
abnormal telencephalon morphology J:140575
decreased anterior commissure size J:140575
decreased hippocampal commissure size J:140575
decreased survivor rate J:140575
postnatal lethality, incomplete penetrance J:140575
small hippocampus J:140575
Emx1tm1(cre)Ito/Emx1+
Tg(CAG-Mtor*)#Atai/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * ICR 		abnormal cerebral cortex morphology J:211789
decreased neuronal precursor cell number J:211789
increased neuron apoptosis J:211789
small hippocampus J:211789
Emx1tm1(cre)Ito/?
Gt(ROSA)26Sortm1(HD*103Q)Xwy/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		normal nervous system phenotype J:99759
Emx1tm1(cre)Krj/Emx1+
Numbtm1Ynj/Numbtm1Ynj
involves: 129S2/SvPas * 129X1/SvJ * CD-1 		no abnormal phenotype detected J:87149
Emx1tm1(cre)Krj/Emx1+
Numbtm1Ynj/Numbtm1Ynj
Numbltm1Wmz/Numbltm1Wmz
involves: 129S2/SvPas * 129X1/SvJ * CD-1 		abnormal brain ventricle morphology J:87149
abnormal cerebral cortex morphology J:87149
abnormal cortical marginal zone morphology J:87149
abnormal embryonic neuroepithelium morphology J:87149
abnormal forebrain morphology J:87149
abnormal hearing physiology J:87149
abnormal hippocampus morphology J:87149
abnormal lateral ventricle morphology J:87149
abnormal neuron differentiation J:87149
abnormal neuron specification J:87149
absent corpus callosum J:87149
circling J:87149
decreased body size J:87149
ectopic cortical neuron J:87149
enlarged brain ventricles J:87149
female infertility J:87149
increased neuron apoptosis J:87149
male infertility J:87149
postnatal lethality, incomplete penetrance J:87149
small thalamus J:87149
social withdrawal J:87149
sporadic seizures J:87149
stereotypic behavior J:87149
Emx1tm1(cre)Krj/Emx1+
Wnt3atm2Eag/Wnt3a+
involves: 129S2/SvPas 		abnormal cerebral cortex morphology J:104373
abnormal suckling behavior J:104373
absent Cajal-Retzius cell J:104373
absent choroid plexus J:104373
postnatal lethality J:104373
short mandible J:104373
Emx1tm1(cre)Krj/Emx1+
Mycbp2tm1Adia/Mycbp2tm1Adia
involves: 129S2/SvPas * C57BL/6 		abnormal axon guidance J:125702
abnormal corpus callosum morphology J:125702
abnormal hippocampus morphology J:125702
decreased corpus callosum size J:125702
enlarged lateral ventricles J:125702
Emx1tm1(cre)Krj/Emx1+
Ptpn11tm6Bgn/Ptpn11+
B6.129S-Ptpn11tm6Bgn Emx1tm1(cre)Krj 		abnormal hippocampus neuron morphology J:242312
abnormal spatial learning J:242312
decreased exploration in new environment J:242312
impaired cued conditioning behavior J:242312
Emx1tm1(cre)Krj/Emx1+
Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo
involves: 129S2/SvPas * C57BL/6 * SJL 		abnormal neocortex morphology J:154611
abnormal olfactory bulb morphology J:154611
abnormal olfactory cortex morphology J:154611
abnormal telencephalon morphology J:154611
telencephalon hypoplasia J:154611
Emx1tm1(cre)Krj/Emx1+
Lhx2tm1.1Ddmo/Lhx2tm1.2Ddmo
involves: 129S2/SvPas * C57BL/6 * SJL 		abnormal neocortex morphology J:154611
abnormal olfactory bulb morphology J:154611
abnormal olfactory cortex morphology J:154611
abnormal telencephalon morphology J:154611
telencephalon hypoplasia J:154611
Emx1tm1(cre)Krj/Emx1+
Gsx2tm2.1Kc/Gsx2tm2.1Kc
involves: 129S6/SvEvTac * C57BL/6 * SJL 		abnormal lateral ganglionic eminence morphology J:154936
abnormal neuron differentiation J:154936
abnormal olfactory bulb morphology J:154936
Emx1tm1(cre)Krj/Emx1+
Gsx2tm2.1Kc/Gsx2tm2.1Kc
Tg(CAG-cat,-EGFP)1Rbns/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL 		abnormal olfactory bulb development J:154936
Emx1tm1(cre)Krj/Emx1+
Esco2tm1.1Ge/Esco2tm1.1Ge
involves: 129S2/SvPas * C57BL/6 * SJL 		abnormal embryonic neuroepithelium morphology J:180371
abnormal hippocampus development J:180371
abnormal neocortex morphology J:180371
abnormal neuronal precursor proliferation J:180371
absent hippocampus J:180371
increased neuron apoptosis J:180371
microcephaly J:180371
Emx1tm1(cre)Krj/Emx1+
Topbp1tm1Pmc/Topbp1tm1Pmc
involves: 129S2/SvPas * C57BL/6J 		abnormal cerebral cortex morphology J:181920
Emx1tm1(cre)Krj/Emx1+
Tg(CMV-GFP,-Smarcc2,-lacZ)#Stoy/0
involves: 129S2/SvPas 		abnormal DNA methylation J:197141
abnormal neocortex morphology J:197141
abnormal neuron differentiation J:197141
abnormal neuron number J:197141
abnormal neuronal precursor cell number J:197141
thin cerebral cortex J:197141
Emx1tm1(cre)Krj/Emx1+
Magohtm1c(KOMP)Dlsi/Magoh+
involves: 129S2/SvPas * C57BL/6J 		microcephaly J:235650
Emx1tm1(cre)Krj/Emx1+
Rbm8atm1Dlsi/Rbm8a+
involves: 129S2/SvPas * C57BL/6J 		abnormal cerebral cortex morphology J:235650
decreased neuron number J:235650
microcephaly J:235650
Emx1tm1(cre)Krj/Emx1+
Rbm8atm1Dlsi/Rbm8a+
involves: C57BL/6J 		abnormal cerebral cortex morphology J:221648
abnormal radial glial cell apoptosis J:221648
abnormal radial glial cell morphology J:221648
abnormal stratification in cerebral cortex J:221648
abnormal telencephalon development J:221648
decreased brain size J:221648
decreased neocortex size J:221648
decreased neuronal precursor cell number J:221648
decreased radial glial cell number J:221648
ectopic cortical neuron J:221648
impaired neuron differentiation J:221648
increased forebrain apoptosis J:221648
increased neuron apoptosis J:221648
increased neuron number J:221648
increased neuronal precursor proliferation J:221648
microcephaly J:221648
premature neuronal precursor differentiation J:221648
small brain ventricles J:221648
thin cerebral cortex J:221648
Emx1tm1(cre)Krj/Emx1+
Rcor2tm1c(EUCOMM)Wtsi/Rcor2tm1c(EUCOMM)Wtsi
involves: 129S2/SvPas * C57BL/6N 		decreased brain size J:235702
thin cerebral cortex J:235702
Emx1tm1(cre)Krj/?
Kcnq2tm1.1Avtz/Kcnq2tm1.1Avtz
involves: 129S2/SvPas * C57BL/6 		abnormal action potential J:208109
abnormal afterhyperpolarization J:208109
abnormal brain wave pattern J:208109
abnormal hippocampus morphology J:208109
abnormal nervous system electrophysiology J:208109
postnatal lethality, incomplete penetrance J:208109
premature death J:208109
tonic-clonic seizures J:208109
Emx1tm1(cre)Krj/?
Kcnq3tm1.1Avtz/Kcnq3tm1.1Avtz
involves: 129S2/SvPas * C57BL/6 		abnormal hippocampus morphology J:208109
abnormal nervous system electrophysiology J:208109
Emx1tm1(cre)Krj/?
Rai1tm2.1Luo/Rai1tm2.1Luo
either: (involves: 129S1/Sv * 129S2/SvPas * C57BL/6) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6) 		no abnormal phenotype detected J:237687
Emx1tm1(cre)Yql/Emx1+
Lhx2tm1Monu/Lhx2tm1Monu
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal cerebral cortex morphology J:130167
Emx1tm1(cre)Yql/Emx1+
Tor1atm2Yql/Tor1atm2Yql
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		abnormal gait J:130483
abnormal motor coordination/balance J:130483
circling J:130483
hyperactivity J:130483
increased stereotypic behavior J:130483
normal nervous system phenotype J:130483
Emx1tm1.1(cre)Ito/Emx1+
Tg(Gfap-GFAP*R239H)60TMIke/0
involves: 129P2/OlaHsd * C57BL/6J 		increased susceptibility to pharmacologically induced seizures J:139349
Emx1tm1.1(cre)Ito/Emx1+
Scn1atm2.1Kzy/Scn1atm2.1Kzy
involves: 129P2/OlaHsd * C57BL/6 		abnormal neocortex morphology J:202863
normal behavior/neurological phenotype J:202863
Emx1tm1.1(cre)Ito/Emx1+
Scn1atm2.1Kzy/Scn1atm2.1Kzy
Tg(Slc32a1-cre)65Kzy/0
involves: 129P2/OlaHsd * C57BL/6 		convulsive seizures J:202863
premature death J:202863
Emx1tm1Sia/Emx1tm1Sia
Emx2tm1Sia/Emx2+
involves: C57BL/6 * CBA 		abnormal cerebral cortex morphology J:163926
abnormal embryonic/fetal subventricular zone morphology J:163926
Emx1tm1Sia/Emx1tm1Sia
Emx2tm1Sia/Emx2tm1Sia
involves: C57BL/6 * CBA 		abnormal pallium development J:163926
absent dentate gyrus J:163926
absent hippocampal fimbria J:163926
absent hippocampus J:163926
Emx1tm1Sia/Emx1tm1Sia
Otx1tm1Sia/Otx1tm1Sia
Not Specified 		normal nervous system phenotype J:98539
Emx1tm1Sia/Emx1tm1Sia
Otx2tm1Sia/Otx2+
involves: C57BL/6 * CBA 		normal nervous system phenotype J:98539
Emx1tm1Sia/Emx1tm1Sia
Rr103tm3.1Sia/Rr103tm3.1Sia
involves: C57BL/6 * CBA 		abnormal cerebral cortex morphology J:163926
abnormal pallium development J:163926
absent dentate gyrus J:163926
small hippocampus J:163926
Emx1tm1Sia/Emx1tm1Sia
Rr103tm3Sia/Rr103tm3Sia
involves: C57BL/6 * CBA 		abnormal cerebral cortex morphology J:163926
abnormal pallium development J:163926
absent dentate gyrus J:163926
small hippocampus J:163926
Epha4tm1.1Bzh/Epha4tm1.2Bzh
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S7/SvEvBrd 		abnormal corticospinal tract morphology J:209606
normal behavior/neurological phenotype J:209606
Fezf2tm1.1Nses/Fezf2tm1.1Nses
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * 129S1/Sv 		abnormal corticospinal tract morphology J:186632
Fgf13tm1Xuzh/Y
Emx1tm1(cre)Yql/Emx1+
involves: 129S2/SvPas 		abnormal axon morphology J:186253
abnormal cerebral cortex pyramidal cell morphology J:186253
abnormal depression-related behavior J:186253
abnormal object recognition memory J:186253
abnormal spatial learning J:186253
abnormal spatial working memory J:186253
behavioral despair J:186253
hyperactivity J:186253
impaired cued conditioning behavior J:186253
increased anxiety-related response J:186253
Glultm1.1Ncd/Glultm1.1Ncd
Emx1tm1(cre)Krj/Emx1+
B6.Cg-Glultm1.1Ncd Emx1tm1(cre)Krj 		abnormal blood vessel physiology J:272643
abnormal brain vasculature morphology J:272643
abnormal locomotor activation J:272643
astrocytosis J:272643
decreased anxiety-related response J:272643
decreased aspartic acid level J:272643
decreased gamma-aminobutyric acid level J:272643
decreased glutamic acid level J:272643
decreased glutamine level J:272643
decreased locomotor activity J:272643
decreased vertical activity J:272643
hippocampus pyramidal cell degeneration J:272643
increased locomotor activity J:272643
neurodegeneration J:272643
premature death J:272643
seizures J:272643
Gm30731tm1.1Dalm/Gm30731tm1.1Dalm
Emx1tm1(cre)Krj/Emx1+
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 		abnormal cerebral cortex morphology J:281278
abnormal neocortex morphology J:281278
abnormal neuronal stem cell physiology J:281278
increased neuron number J:281278
Islr2tm1.1Ddg/Islr2tm2.1Ddg
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * SJL 		abnormal brain internal capsule morphology J:210221
abnormal brain morphology J:210221
abnormal telencephalon development J:210221
premature death J:210221
Itgb1tm1Mll/Itgb1tm1Mll
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129X1/SvJ 		abnormal Cajal-Retzius cell morphology J:170581
abnormal radial glial cell morphology J:170581
normal nervous system phenotype J:170581
radial glial endfoot detachment J:170581
Kat6atm1c(EUCOMM)Wtsi/Kat6atm1c(EUCOMM)Wtsi
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J * C57BL/6N * CD-1 		no abnormal phenotype detected J:224155
Knl1tm1c(EUCOMM)Hmgu/Knl1tm1c(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6N 		decreased neuron number J:278483
microcephaly J:278483
telencephalon hypoplasia J:278483
Magohtm1c(KOMP)Dlsi/Magoh+
Emx1tm1(cre)Krj/Emx1+
B6.Cg-Magohtm1c(KOMP)Dlsi Emx1tm1(cre)Krj 		decreased brain size J:213515
thin cerebral cortex J:213515
Mpp3tm1.1Wij/Mpp3tm1.1Wij
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J 		abnormal cerebral cortex morphology J:198427
abnormal mitotic spindle morphology J:198427
abnormal neuronal migration J:198427
increased mitotic index J:198427
Nr2f1tm2.1Mist/Nr2f1tm2.1Mist
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J 		abnormal barrel cortex morphology J:127387
abnormal cerebral cortex morphology J:127387
abnormal primary somatosensory cortex morphology J:127387
normal nervous system phenotype J:127387
Nrg1tm1Fej/Nrg1tm1Fej
Emx1tm1(cre)Krj/?
involves: 129P2/OlaHsd * 129S2/SvPas 		normal nervous system phenotype J:145464
Orc3tm1.1Zhua/Orc3tm1.1Zhua
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas 		abnormal radial glial cell morphology J:170581
decreased neuronal precursor proliferation J:170581
decreased radial glial cell number J:170581
normal nervous system phenotype J:170581
Pals1tm1Caw/Pals1+
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas 		abnormal behavior J:160624
abnormal cerebral cortex morphology J:160624
abnormal neuronal precursor proliferation J:160624
premature neuronal precursor differentiation J:160624
small hippocampus J:160624
Pals1tm1Caw/Pals1tm1Caw
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas 		abnormal brain morphology J:160624
abnormal cerebral cortex morphology J:160624
abnormal gait J:160624
abnormal neuronal precursor proliferation J:160624
abnormal placing response J:160624
abnormal spatial learning J:160624
normal behavior/neurological phenotype J:160624
decreased body weight J:160624
decreased exploration in new environment J:160624
decreased grip strength J:160624
decreased locomotor activity J:160624
disheveled coat J:160624
increased neuron apoptosis J:160624
jerky movement J:160624
jumpy J:160624
loss of cortex neurons J:160624
normal mortality/aging J:160624
premature neuronal precursor differentiation J:160624
normal reproductive system phenotype J:160624
thin cerebral cortex J:160624
Pals1tm1Caw/Pals1tm1Caw
Tsc2tm1.1Mjg/Tsc2tm1.1Mjg
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ 		abnormal cerebral cortex morphology J:160624
Pax6tm2Pgr/Pax6tm2Pgr
Smarcc2tm1.1Stoy/Smarcc2+
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 		abnormal neuron number J:197141
normal nervous system phenotype J:197141
Pax6tm2Pgr/Pax6tm2Pgr
Smarcc2tm1.1Stoy/Smarcc2tm1.1Stoy
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 		abnormal neocortex morphology J:197141
abnormal neuron number J:197141
abnormal neuronal precursor cell number J:197141
Pdcd10tm1Wami/Pdcd10tm1Wami
Emx1tm1(cre)Krj/Emx1+
involves: 129 * 129S2/SvPas * C57BL/6 		abnormal brain vasculature morphology J:170480
astrocytosis J:170480
increased brain size J:170480
increased hemangioma incidence J:170480
normal mortality/aging J:170480
Pik3r4mbe/Pik3r4tm1.1Mpnd
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C3H/HeH * C57BL/6 		abnormal hippocampus pyramidal cell layer J:258027
abnormal hippocampus stratum oriens morphology J:258027
ectopic hippocampus pyramidal cells J:258027
Pik3r4tm1.1Mpnd/Pik3r4tm1.1Mpnd
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6 		abnormal cerebral cortex morphology J:258027
abnormal hippocampus morphology J:258027
thin cerebral cortex J:258027
Pnkptm1.1Pmc/Pnkptm1.1Pmc
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 		abnormal cerebellar cortex morphology J:226703
decreased body size J:226703
decreased brain size J:226703
decreased cell proliferation J:226703
increased brain apoptosis J:226703
Pomt2tm1.1Hhu/Pomt2tm1.1Hhu
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J 		abnormal Ammon gyrus morphology J:179356
abnormal basement membrane morphology J:179356
abnormal Cajal-Retzius cell morphology J:179356
abnormal dentate gyrus morphology J:179356
abnormal forebrain morphology J:179356
abnormal hippocampus CA3 region morphology J:179356
abnormal hippocampus layer morphology J:179356
abnormal neocortex morphology J:179356
abnormal radial glial cell morphology J:179356
astrocytosis J:179356
Ppp4r3aem1Qili/Ppp4r3aem1Qili
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J 		abnormal miniature excitatory postsynaptic currents J:326388
abnormal sucrose solution preference J:326388
normal behavior/neurological phenotype J:326388
behavioral despair J:326388
decreased dendritic spine density J:326388
decreased neurotransmitter release J:326388
increased anxiety-related response J:326388
increased thigmotaxis J:326388
Ptbp1tm1Nobu/Ptbp1tm2Nobu
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd 		abnormal brain ependyma motile cilium morphology J:213479
abnormal telencephalon morphology J:213479
dilated lateral ventricle J:213479
hydrocephaly J:213479
Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal mitral cell morphology J:207976
abnormal olfactory bulb layer morphology J:207976
absent corpus callosum J:207976
decreased body size J:207976
enlarged lateral ventricles J:207976
neurodegeneration J:207976
neuron degeneration J:207976
postnatal growth retardation J:207976
postnatal lethality, complete penetrance J:207976
slow postnatal weight gain J:207976
small hippocampus J:207976
thin cerebral cortex J:207976
Rem2tm1c(EUCOMM)Hmgu/Rem2tm1c(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6N 		abnormal visual cortex morphology J:263600
Rnu11tm1.1Rank/Rnu11tm1.1Rank
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129X1/SvJ 		abnormal pallium development J:266583
absent hippocampus J:266583
decreased neuron number J:266583
decreased neuronal precursor cell number J:266583
decreased radial glial cell number J:266583
increased cell death J:266583
microcephaly J:266583
Robo4tm1.1Xby/Robo4tm1.1Xby
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * C57BL/6 		normal nervous system phenotype J:202213
Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 		normal behavior/neurological phenotype J:201156
Slc17a6tm1.1Jder/Slc17a6tm1.1Jder
Emx1tm1(cre)Krj/Emx1+
B6.Cg-Emx1tm1(cre)Krj Slc17a6tm1.1Jder 		abnormal dendrite morphology J:192240
abnormal dendritic spine morphology J:192240
abnormal glutamate-mediated receptor currents J:192240
abnormal spatial learning J:192240
abnormal spatial reference memory J:192240
decreased body size J:192240
decreased synaptic glutamate release J:192240
increased exploration in new environment J:192240
increased paired-pulse ratio J:192240
reduced long-term depression J:192240
Smarcc2tm1.1Stoy/Smarcc2tm1.1Stoy
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 		abnormal DNA methylation J:197141
abnormal neocortex morphology J:197141
abnormal neuron differentiation J:197141
abnormal neuronal precursor cell number J:197141
abnormal neuronal precursor proliferation J:197141
thickened cerebral cortex J:197141
Sp2tm1.1Htg/Sp2tm1.1Htg
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas 		abnormal cortical plate morphology J:194076
abnormal cortical ventricular zone morphology J:194076
abnormal embryonic/fetal subventricular zone morphology J:194076
abnormal neuron differentiation J:194076
prenatal lethality, incomplete penetrance J:194076
Tor1atm1Wtd/Tor1atm3.1Wtd
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J 		gliosis J:213785
impaired coordination J:213785
limb grasping J:288753
neurodegeneration J:213785
thin cerebral cortex J:288753
Tor1atm1Wtd/Tor1atm3.1Wtd
Tor1btm1.2Wtd/Tor1btm1.1Wtd
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J 		gliosis J:288753
neurodegeneration J:288753
postnatal growth retardation J:288753
premature death J:288753
thin cerebral cortex J:288753
Tor1atm2Wtd/Tor1atm3.1Wtd
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J 		normal nervous system phenotype J:288753
Tor1atm2Wtd/Tor1atm3.1Wtd
Tor1btm1.2Wtd/Tor1b+
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J 		limb grasping J:288753
thin cerebral cortex J:288753
Tor1atm2Wtd/Tor1atm3.1Wtd
Tor1btm1.2Wtd/Tor1btm1.2Wtd
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J 		thin cerebral cortex J:288753
Tsc2tm1.1Kcess/Tsc2tm1.1Kcess
Emx1tm1(cre)Krj/Emx1+
involves: 129S/Sv * C57BL/6J 		decreased body weight J:195049
environmentally induced seizures J:195049
postnatal growth retardation J:195049
postnatal lethality, complete penetrance J:195049
Zfp335tm1.1Caw/Zfp335+
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 		thin cerebral cortex J:193339
Zfp335tm1.1Caw/Zfp335tm1.1Caw
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 		decreased brain size J:193339
loss of cortex neurons J:193339
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10/29/2024
MGI 6.24 		The Jackson Laboratory