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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		En1
engrailed 1
MGI:95389
143 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ankrd16tm1.1Slac/Ankrd16tm1.2Slac
En1tm2(cre)Wrst/En1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		neuron degeneration J:262421
Purkinje cell degeneration J:262421
Atg7tm1Tchi/Atg7tm1Tchi
En1tm2(cre)Wrst/En1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj 		abnormal brain morphology J:192452
abnormal gait J:192452
abnormal locomotor behavior J:192452
abnormal neuron morphology J:192452
abnormal substantia nigra pars compacta morphology J:192452
astrocytosis J:192452
ataxia J:192452
decreased dopamine level J:192452
decreased survivor rate J:192452
neuron degeneration J:192452
premature death J:192452
Purkinje cell degeneration J:192452
tremors J:192452
weight loss J:192452
Dnm1ltm1.1Hise/Dnm1ltm1.1Hise
En1tm2(cre)Wrst/En1+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal cerebellar Purkinje cell layer J:153835
abnormal cerebellum development J:153835
abnormal Purkinje cell mitochondrial morphology J:153835
absent gastric milk in neonates J:153835
decreased Purkinje cell number J:153835
postnatal lethality, complete penetrance J:153835
reduced cerebellar foliation J:153835
small cerebellum J:153835
Dnm1ltm1.1Hise/Dnm1ltm1.2Hise
En1tm2(cre)Wrst/En1+
involves: 129 * C57BL/6 * FVB/N * SJL 		abnormal cerebellar Purkinje cell layer J:153835
abnormal cerebellum development J:153835
abnormal Purkinje cell mitochondrial morphology J:153835
absent gastric milk in neonates J:153835
decreased Purkinje cell number J:153835
postnatal lethality, complete penetrance J:153835
reduced cerebellar foliation J:153835
small cerebellum J:153835
Drd2tm3.1Ebo/Drd2tm3.1Ebo
En1tm2(cre)Wrst/En1+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal dopamine level J:185643
abnormal nervous system electrophysiology J:185643
decreased physiological sensitivity to xenobiotic J:185643
enhanced behavioral response to anesthetic J:185643
enhanced behavioral response to cocaine J:185643
enhanced behavioral response to xenobiotic J:185643
hyperactivity J:185643
increased dopamine level J:185643
increased vertical activity J:185643
induced hyperactivity J:185643
En1em1Smun/En1+
Gm29348em4Smun/Gm29348+
involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1 		abnormal limb morphology J:306235
normal nervous system phenotype J:306235
normal skeleton phenotype J:306235
En1tm1.1(Wnt1)Wrst/En1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		increased inferior colliculus size J:91004
neonatal lethality, complete penetrance J:91004
En1tm1Alj/En1+
En2tm1Alj/En2tm1Alj
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ 		normal nervous system phenotype J:84363
En1tm1Alj/En1tm1Alj
En2tm1Alj/En2+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ 		absent cerebellum J:84363
En1tm1Alj/En1tm1Alj
Moen1C57BL/6/Moen1C57BL/6
involves: 129S1/Sv * C57BL/6 		abnormal cerebellum development J:120598
En1tm1Alj/En1tm1Alj
Moen2C57BL/6/Moen2C57BL/6
involves: 129S1/Sv * C57BL/6 		abnormal cerebellum development J:120598
En1tm1Alj/En1tm1Alj
Moen3C57BL/6/Moen3C57BL/6
involves: 129S1/Sv * C57BL/6 		abnormal cerebellum development J:120598
En1tm1Alj/En1tm1Alj
Rfngtm1Tfv/Rfng+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal apical ectodermal ridge morphology J:149312
En1tm1Alj/En1tm1Alj
Rfngtm1Tfv/Rfngtm1Tfv
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal apical ectodermal ridge morphology J:149312
abnormal limb development J:149312
En1tm1Alj/En1tm1Alj
Wnt7atm1Amc/Wnt7atm1Amc
Tg(Wnt1-En1)1Amc/0
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) 		abnormal autopod morphology J:45301
abnormal digit morphology J:45301
abnormal foot pad morphology J:45301
abnormal forelimb morphology J:45301
oligodactyly J:45301
perinatal lethality, incomplete penetrance J:45301
premature death J:45301
En1tm1Alj/En1tm3(En2)Alj
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) 		no abnormal phenotype detected J:27767
En1tm1Alj/En1tm8.1Alj
En2tm1Alj/En2tm6Alj
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+
involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster 		abnormal cerebellar foliation J:156169
abnormal cerebellar granule cell precursor proliferation J:156169
abnormal cerebellum development J:156169
abnormal cerebellum external granule cell layer morphology J:156169
abnormal cerebellum fissure morphology J:156169
abnormal cerebellum morphology J:156169
abnormal cerebellum posterior vermis morphology J:156169
abnormal cerebellum vermis lobule morphology J:156169
abnormal cerebellum vermis morphology J:156169
abnormal midbrain morphology J:156169
cerebellum vermis hypoplasia J:156169
decreased anterior vermis size J:156169
perinatal lethality, complete penetrance J:156169
small cerebellum J:156169
thin external granule cell layer J:156169
En1tm1Alj/En1tm8.1Alj
En2tm1Alj/En2tm7.1Alj
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster 		abnormal cerebellar foliation J:156169
abnormal cerebellum hemisphere lobule morphology J:156169
abnormal cerebellum vermis lobule morphology J:156169
En1tm1Alj/En1tm8.1Alj
En2tm1Alj/En2tm7.1Alj
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster 		abnormal cerebellar foliation J:156169
abnormal cerebellum hemisphere lobule morphology J:156169
abnormal cerebellum vermis lobule morphology J:156169
En1tm1Alj/En1tm8.1Alj
En2tm6Alj/En2+
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster 		abnormal cerebellar foliation J:156169
abnormal cerebellum vermis lobule morphology J:156169
decreased anterior vermis size J:156169
En1tm1Gld/En1+
En2tm1Alj/En2tm1Alj
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster 		abnormal behavior J:115270
decreased dopamine level J:115270
decreased food intake J:115270
decreased grip strength J:115270
decreased locomotor activity J:115270
decreased neurotransmitter release J:115270
loss of dopaminergic neurons J:115270
slow postnatal weight gain J:115270
En1tm1Gld/En1+
Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		abnormal axon extension J:52637
abnormal axon guidance J:52637
En1tm1Gld/En1tm1Gld
En2tm1Alj/En2+
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster 		decreased dopaminergic neuron number J:115270
perinatal lethality, complete penetrance J:115270
En1tm1Gld/En1tm1Gld
En2tm1Alj/En2tm1Alj
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster 		decreased dopaminergic neuron number J:115270
perinatal lethality, complete penetrance J:115270
En1tm2(cre)Gld/En1+
Gli2tm1Alj/Gli2tm6Alj
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster 		abnormal cerebellar granule layer morphology J:108507
abnormal cerebellar lobule formation J:108507
abnormal cerebellar molecular layer J:108507
abnormal cerebellar Purkinje cell layer J:108507
abnormal cerebellum anterior vermis morphology J:108507
abnormal cerebellum external granule cell layer morphology J:108507
abnormal cerebellum vermis morphology J:108507
abnormal gait J:108507
decreased body size J:108507
impaired balance J:108507
normal nervous system phenotype J:108507
small cerebellum J:108507
thin external granule cell layer J:108507
tremors J:108507
En1tm2(cre)Gld/En1+
Gli1tm2Alj/Gli1tm2Alj
Gli2tm1Alj/Gli2tm6Alj
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster 		abnormal cerebellar foliation J:108507
abnormal cerebellum development J:108507
abnormal cerebellum morphology J:108507
En1tm2(cre)Gld/En1+
Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd * 129S1/Sv 		abnormal CNS synaptic transmission J:106437
abnormal ventral interneuron 1 morphology J:106437
En1tm2(cre)Gld/En1+
Tg(CAG-Bgeo,-AlstR,-EGFP)192Gld/0
involves: 129S1/Sv 		abnormal CNS synaptic transmission J:106437
En1tm2(cre)Wrst/En1+
Gbx2tm1.1Mrt/Gbx2tm1.1Alj
involves: 129/Sv * C57BL/6 * SJL * Swiss Webster 		abnormal cerebellar foliation J:79431
abnormal cerebellum development J:79431
abnormal midbrain development J:79431
abnormal midbrain-hindbrain boundary morphology J:79431
abnormal postnatal growth J:79431
cerebellum vermis hypoplasia J:79431
decreased body weight J:79431
decreased embryonic neuroepithelial cell proliferation J:79431
decreased embryonic neuroepithelium thickness J:79431
increased inferior colliculus size J:79431
normal mortality/aging J:79431
normal nervous system phenotype J:79431
postnatal lethality, incomplete penetrance J:79431
En1tm2(cre)Wrst/En1+
Lhx1tm2.1Bhr/Lhx1tm2.1Bhr
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ 		no abnormal phenotype detected J:123471
En1tm2(cre)Wrst/En1+
Lhx1tm1Tmj/Lhx1tm2.1Bhr
Lhx5tm1Lmgd/Lhx5tm1Lmgd
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ 		absent Purkinje cell layer J:123471
decreased Purkinje cell number J:123471
small cerebellum J:123471
En1tm2(cre)Wrst/En1+
Fgfr1tm1Jpa/Fgfr1tm1Jpa
involves: 129S1/Sv * 129X1/SvJ 		abnormal cerebellum morphology J:83004
abnormal gait J:83004
abnormal locus ceruleus morphology J:83004
abnormal midbrain morphology J:83004
abnormal posture J:83004
abnormal trochlear nerve morphology J:83004
absent cerebellum vermis J:83004
absent inferior colliculus J:83004
impaired coordination J:83004
En1tm2(cre)Wrst/En1+
Mfn2tm1Dcc/Mfn2tm3Dcc
involves: 129 * 129S4/SvJaeSor * Black Swiss 		abnormal neuron mitochondrial morphology J:132329
abnormal Purkinje cell dendrite morphology J:132329
decreased body size J:132329
impaired limb coordination J:132329
impaired righting response J:132329
increased neuron apoptosis J:132329
postnatal lethality, complete penetrance J:132329
Purkinje cell degeneration J:132329
small cerebellum J:132329
En1tm2(cre)Wrst/En1+
Tor1atm1Wtd/Tor1atm3.1Wtd
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J 		abnormal red nucleus morphology J:213785
decreased body weight J:213785
decreased neuron number J:213785
dystonia J:213785
gliosis J:213785
limb grasping J:213785
neurodegeneration J:213785
En1tm2(cre)Wrst/En1+
Tor1atm2Wtd/Tor1atm3.1Wtd
involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL 		abnormal facial nerve morphology J:213785
abnormal red nucleus morphology J:213785
decreased neuron number J:213785
dystonia J:213785
gliosis J:213785
impaired coordination J:213785
limb grasping J:213785
neurodegeneration J:213785
En1tm2(cre)Wrst/En1+
Fgfr2tm1Wrst/Fgfr2tm1Wrst
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal nervous system phenotype J:118802
En1tm2(cre)Wrst/En1+
Gata2tm1Msal/Gata2tm1Msal
involves: 129S1/Sv * 129X1/SvJ 		abnormal GABAergic neuron morphology J:143527
abnormal neuron differentiation J:143527
abnormal serotonergic neuron morphology J:143527
normal nervous system phenotype J:143527
En1tm2(cre)Wrst/En1tm8.1Alj
En2tm2Alj/En2+
involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster 		absent cerebellum J:134516
absent inferior colliculus J:134516
decreased superior colliculus size J:134516
En1tm2(cre)Wrst/En1tm8.1Alj
En2tm2Alj/En2tm2Alj
involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster 		absent cerebellum J:134516
absent colliculi J:134516
absent inferior colliculus J:134516
absent superior colliculus J:134516
absent tectum J:134516
En1tm2(cre)Wrst/?
Gli3tm1Alj/Gli3tm1Alj
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 		abnormal cerebellar foliation J:137136
abnormal hindbrain morphology J:137136
abnormal rhombomere morphology J:137136
abnormal tectum morphology J:137136
enlarged cerebral aqueduct J:137136
enlarged tectum J:137136
normal nervous system phenotype J:137136
En1tm2(cre)Wrst/?
Gli3tm1Alj/Gli3tm1Alj
Smotm2Amc/Smotm2Amc
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 		abnormal cerebellar foliation J:137136
abnormal cerebellum morphology J:137136
abnormal hindbrain morphology J:137136
abnormal rhombomere morphology J:137136
abnormal tectum morphology J:137136
enlarged cerebral aqueduct J:137136
enlarged tectum J:137136
normal nervous system phenotype J:137136
small cerebellum J:137136
thin external granule cell layer J:137136
En1tm2(cre)Wrst/?
Gt(ROSA)26Sortm5(CAG-EGFP,-lacZ)Dym/?
Nkx2-2tm1Jlr/Nkx2-2tm1Jlr
Tg(Fev-flpe)1Dym/?
involves: 129S1/Sv * 129X1/SvJ 		abnormal rhombomere morphology J:136096
En1tm2(cre)Wrst/?
Gt(ROSA)26Sortm5(CAG-EGFP,-lacZ)Dym/?
Tg(Fev-flpe)1Dym/?
involves: 129S1/Sv * 129X1/SvJ 		no abnormal phenotype detected J:136096
En1tm2Alj/En1+
En2tm2Alj/En2+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		abnormal cerebellar foliation J:134516
abnormal cerebellum anterior vermis morphology J:134516
abnormal cerebellum posterior vermis morphology J:134516
abnormal cerebellum vermis morphology J:134516
small cerebellum J:134516
En1tm2Alj/En1+
En2tm2Alj/En2tm2Alj
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		abnormal cerebellar foliation J:134516
abnormal cerebellum anterior vermis morphology J:134516
abnormal cerebellum morphology J:134516
abnormal cerebellum posterior vermis morphology J:134516
abnormal tectum morphology J:134516
absent cerebellum J:134516
absent cerebellum vermis J:134516
absent inferior colliculus J:134516
decreased inferior colliculus size J:134516
normal mortality/aging J:134516
small cerebellum J:134516
small tectum J:134516
En1tm2Alj/En1tm2Alj
En2tm2Alj/En2+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		absent cerebellum J:134516
absent colliculi J:134516
absent inferior colliculus J:134516
absent superior colliculus J:134516
absent tectum J:134516
perinatal lethality, complete penetrance J:134516
En1tm2Alj/En1tm2Alj
En2tm2Alj/En2tm2Alj
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		abnormal midbrain-hindbrain boundary development J:66592
absent colliculi J:134516
absent inferior colliculus J:134516
absent midbrain J:66592
absent midbrain-hindbrain boundary J:66592
absent rhombomere 1 J:66592
absent superior colliculus J:134516
absent tectum J:134516
decreased rhombomere 1 size J:66592
small cerebellum J:134516
En1tm2Alj/En1tm3(En2)Alj
En2tm2Alj/En2tm2Alj
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		abnormal cerebellar foliation J:134516
abnormal cerebellum morphology J:134516
abnormal cerebellum posterior vermis morphology J:134516
decreased inferior colliculus size J:134516
small cerebellum J:134516
En1tm3(En2)Alj/En1tm3(En2)Alj
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal apical ectodermal ridge morphology J:34307
abnormal foot pad morphology J:34307
abnormal limb morphology J:34307
abnormal nail morphology J:34307
En1tm3(En2)Alj/En1tm3(En2)Alj
involves: 129S1/Sv * 129X1/SvJ * Swiss Webster 		normal nervous system phenotype J:134516
En1tm3(En2)Alj/En1tm3(En2)Alj
En2tm2Alj/En2+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		normal nervous system phenotype J:134516
En1tm3(En2)Alj/En1tm3(En2)Alj
En2tm2Alj/En2tm2Alj
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		abnormal cerebellar foliation J:134516
abnormal cerebellum morphology J:134516
normal mortality/aging J:134516
small cerebellum J:134516
En1tm3.1(En2)Alj/En1tm3.1(En2)Alj
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal digit pigmentation J:50311
deformed nails J:50311
En1tm5(en)Alj/En1+
En2tm2Alj/En2tm2Alj
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		abnormal cerebellar foliation J:134516
abnormal cerebellum morphology J:134516
abnormal cerebellum posterior vermis morphology J:134516
decreased inferior colliculus size J:134516
small cerebellum J:134516
En1tm5(en)Alj/En1tm5(en)Alj
En2tm2Alj/En2+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		abnormal cerebellum anterior vermis morphology J:134516
abnormal cerebellum posterior vermis morphology J:134516
decreased inferior colliculus size J:134516
decreased survivor rate J:134516
small cerebellum J:134516
En1tm5(en)Alj/En1tm5(en)Alj
En2tm2Alj/En2tm2Alj
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster 		absent cerebellum J:134516
absent inferior colliculus J:134516
absent superior colliculus J:134516
decreased superior colliculus size J:134516
perinatal lethality, complete penetrance J:134516
En1tm7(cre/ESR1)Alj/En1+
En2tm2Alj/En2tm2Alj
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster 		abnormal cerebellum morphology J:134516
abnormal cerebellum vermis morphology J:134516
abnormal tectum morphology J:134516
decreased midbrain size J:134516
decreased rhombomere 1 size J:134516
En1tm7(cre/ESR1)Alj/0
Fgf8tm1.1Jyhl/Fgf8tm1.3Mrt
involves: 129P2/OlaHsd * 129S6/SvEvTac 		abnormal midbrain morphology J:156717
abnormal neural tube morphology J:156717
abnormal Raphe nucleus morphology J:156717
abnormal rhombomere morphology J:156717
abnormal serotonergic neuron morphology J:156717
abnormal substantia nigra morphology J:156717
decreased dopaminergic neuron number J:156717
perinatal lethality, complete penetrance J:156717
small cerebellum J:156717
En1tm7(cre/ESR1)Alj/0
Fgf8tm1.3Mrt/Fgf8tm1.4Mrt
involves: 129P2/OlaHsd * 129S6/SvEvTac 		abnormal midbrain morphology J:156717
abnormal Raphe nucleus morphology J:156717
abnormal serotonergic neuron morphology J:156717
abnormal substantia nigra morphology J:156717
decreased dopaminergic neuron number J:156717
small cerebellum J:156717
En1tm7(cre/ESR1)Alj/0
Fgf8tm1.3Mrt/Fgf8tm2.1Jyhl
Gt(ROSA)26Sortm1Sor/0
involves: 129P2/OlaHsd * 129S6/SvEvTac 		normal growth/size/body region phenotype J:156717
normal nervous system phenotype J:156717
En1tm8.1Alj/En1+
En2tm6Alj/En2+
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * Swiss Webster 		abnormal cerebellar foliation J:156169
abnormal cerebellum fissure morphology J:156169
abnormal cerebellum posterior vermis morphology J:156169
Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+
En1tm2(cre)Wrst/En1+
Tg(ACTFLPe)9205Dym/0
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * SJL 		perinatal lethality J:154944
Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym/Gt(ROSA)26Sor+
En1tm2(cre)Wrst/En1+
Tg(Fev-flpe)1Dym/0
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ 		abnormal axon morphology J:154944
normal behavior/neurological phenotype J:154944
decreased anxiety-related response J:154944
Hbs1ltm1c(KOMP)Wtsi/Hbs1ltm1c(KOMP)Wtsi
En1tm2(cre)Wrst/En1+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6NTac 		abnormal cerebellar foliation J:306384
abnormal cerebellum morphology J:306384
abnormal GABAergic neuron morphology J:306384
decreased neuronal precursor cell number J:306384
decreased Purkinje cell number J:306384
increased neuronal precursor proliferation J:306384
small cerebellum J:306384
Pelotm1Slac/Pelotm1Slac
En1tm2(cre)Wrst/En1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal brain interneuron morphology J:306384
abnormal cerebellum external granule cell layer morphology J:306384
cerebellum hypoplasia J:306384
decreased inferior colliculus size J:306384
decreased Purkinje cell number J:306384
decreased superior colliculus size J:306384
increased neuron apoptosis J:306384
increased neuronal precursor proliferation J:306384
loss of GABAergic neurons J:306384
Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
En1tm2(cre)Wrst/En1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal behavior/neurological phenotype J:201156
Upf2tm1Btp/Upf2tm1Btp
En1tm2(cre)Wrst/En1+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal cerebellum external granule cell layer morphology J:306384
cerebellum hypoplasia J:306384
decreased inferior colliculus size J:306384
decreased superior colliculus size J:306384
increased neuron apoptosis J:306384
increased neuronal precursor proliferation J:306384
loss of GABAergic neurons J:306384
Wnt1tm1.1Mze/Wnt1tm1.1Mze
En1tm2(cre)Wrst/En1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		abnormal midbrain morphology J:194842
decreased midbrain size J:194842
decreased rhombomere 1 size J:194842
Wnt1tm1.1Mze/Wnt1tm1.1Mze
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
En1tm2(cre)Wrst/En1+
involves: 129 * C57BL/6N 		abnormal hindbrain morphology J:194842
abnormal innervation J:194842
abnormal midbrain morphology J:194842
abnormal rhombomere morphology J:194842
decreased neuron number J:194842
decreased neuronal precursor cell number J:194842
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory