Ercc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2
MGI:95413

75 phenotypes from 6 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ercc2^Mhdarco15/Ercc2⁺ C3HeB/FeJ-Ercc2^Mhdarco15	abnormal response to radiation	J:223515
Ercc2^Mhdarco15/Ercc2^Mhdarco15 C3HeB/FeJ-Ercc2^Mhdarco15	abnormal lens morphology	J:223515
	decreased body size	J:223515
	developmental cataract	J:223515
	female infertility	J:223515
	lens vacuoles	J:223515
	microphthalmia	J:223515
	nuclear cataract	J:223515
	normal reproductive system phenotype	J:223515
	rough coat	J:223515
	small lens	J:223515
Ercc2^tm1Jhjh/Ercc2^tm1Jhjh involves: 129P2/OlaHsd * C57BL/6	embryonic lethality before implantation, complete penetrance	J:45017
Ercc2^tm1Jhjh/Ercc2^{tm2(ERCC2)Jhjh} involves: 129P2/OlaHsd * C57BL/6	abnormal hair cuticle	J:48256
	abnormal hair follicle morphology	J:48256
	abnormal hemoglobin	J:48256
	acanthosis	J:48256
	alopecia	J:48256
	anemia	J:48256
	brittle hair	J:48256
	cachexia	J:48256
	decreased erythrocyte cell number	J:48256
	decreased hematocrit	J:48256
	decreased total body fat amount	J:48256
	greasy coat	J:48256
	hyperkeratosis	J:48256
	increased cellular sensitivity to ultraviolet irradiation	J:116054
	increased incidence of tumors by chemical induction	J:48256
	increased incidence of tumors by UV-induction	J:48256
	increased skin tumor incidence	J:48256
	postnatal growth retardation	J:48256
	premature death	J:48256
	scaly skin	J:48256
	thick skin	J:48256
	tremors	J:48256
Ercc2^tm1Jmch/Ercc2^tm1Jmch involves: 129P2/OlaHsd * C57BL/6	embryonic lethality before implantation, complete penetrance	J:116054
Ercc2^tm1Jmch/Ercc2^{tm2(ERCC2)Jhjh} involves: 129P2/OlaHsd * C57BL/6	decreased cellular sensitivity to ultraviolet irradiation	J:116054
	focal dorsal hair loss	J:116054
	normal growth/size/body region phenotype	J:116054
	normal mortality/aging	J:116054
Ercc2^{tm2(ERCC2)Jhjh}/Ercc2^{tm2(ERCC2)Jhjh} involves: 129P2/OlaHsd	normal immune system phenotype	J:47993
	increased cellular sensitivity to ultraviolet irradiation	J:145759
Ercc2^{tm2(ERCC2)Jhjh}/Ercc2^{tm2(ERCC2)Jhjh} involves: 129P2/OlaHsd * C57BL/6	abnormal cell physiology	J:112689
	abnormal circulating amino acid level	J:76608
	abnormal coat/ hair morphology	J:48256
	abnormal epidermis stratum granulosum morphology	J:116054
	abnormal fat cell morphology	J:48256
	abnormal hair follicle morphology	J:48256
	abnormal ovulation	J:76608
	abnormal sebaceous gland morphology	J:116054
	abnormal skeleton morphology	J:48256
	acanthosis	J:48256, J:116054
	alopecia	J:48256
	anemia	J:76608, J:116054
	brittle hair	J:48256, J:116054
	cachexia	J:48256, J:76608, J:116054
	decreased bone mineral density	J:76608
	decreased erythrocyte cell number	J:76608
	decreased hematocrit	J:76608
	decreased hemoglobin content	J:76608
	disproportionate dwarf	J:48256
	enlarged hair follicles	J:48256
	enlarged sebaceous gland	J:76608
	enlarged spleen	J:76608
	greasy coat	J:48256, J:116054
	hyperkeratosis	J:48256, J:116054
	increased incidence of induced tumors	J:48256
	kyphosis	J:76608, J:116054
	normal neoplasm	J:112689
	osteoporosis	J:76608, J:116054
	postnatal growth retardation	J:48256, J:116054
	premature aging	J:76608
	premature death	J:48256, J:116054
	reduced female fertility	J:48256, J:76608
	scaly skin	J:48256
	sparse hair	J:116054
	thick skin	J:48256
	tremors	J:48256
	white spotting	J:76608
Ercc2^{tm2(ERCC2)Jhjh}/Ercc2^tm2Jmch involves: 129P2/OlaHsd * C57BL/6	anemia	J:116054
	brittle hair	J:116054
	decreased cellular sensitivity to ultraviolet irradiation	J:116054
	focal dorsal hair loss	J:116054
	normal growth/size/body region phenotype	J:116054
	normal integument phenotype	J:116054
	normal mortality/aging	J:116054
	postnatal growth retardation	J:116054
	normal skeleton phenotype	J:116054
Ercc2^{tm2(ERCC2)Jhjh}/Ercc2^tm3Jhjh involves: 129P2/OlaHsd * C57BL/6	normal integument phenotype	J:116054
Ercc2^tm2Jmch/Ercc2^tm2Jmch involves: 129P2/OlaHsd * C57BL/6	embryonic lethality before implantation, complete penetrance	J:116054
Ercc2^tm3Jhjh/Ercc2^tm3Jhjh involves: 129 * C57BL/6J	astrocytosis	J:179808
Ercc2^tm3Jhjh/Ercc2^tm3Jhjh involves: 129 * C57BL/6J	microgliosis	J:179808
Ercc2^tm3Jhjh/Ercc2^tm3Jhjh involves: 129P2/OlaHsd * C57BL/6	increased cellular sensitivity to ultraviolet irradiation	J:116054
Ercc2^tm3Jhjh/Ercc2^tm3Jhjh involves: 129P2/OlaHsd * C57BL/6 * FVB	abnormal DNA repair	J:112689
	abnormal testis morphology	J:112689
	acanthosis	J:112689
	cachexia	J:112689
	cornea opacity	J:112689
	decreased exploration in new environment	J:112689
	decreased tumor latency	J:112689
	normal hematopoietic system phenotype	J:112689
	increased cellular sensitivity to ultraviolet irradiation	J:112689
	increased incidence of tumors by UV-induction	J:112689
	normal integument phenotype	J:112689
	limb grasping	J:112689
	normal nervous system phenotype	J:112689
	postnatal growth retardation	J:112689
	premature death	J:112689
	reddish skin	J:112689
	normal reproductive system phenotype	J:112689
	skin photosensitivity	J:112689

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