Ercc3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ercc3
excision repair cross-complementing rodent repair deficiency, complementation group 3
MGI:95414

15 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ercc3^tm1.1Gima/Ercc3^tm1.1Gima either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB)	normal cellular phenotype	J:154596
	normal mortality/aging	J:154596
	normal neoplasm	J:154596
	normal reproductive system phenotype	J:154596
Ercc3^{tm1b(NCOM)Mfgc}/Ercc3⁺ C57BL/6N-Ercc3^{tm1b(NCOM)Mfgc}/Tcp	decreased mean corpuscular hemoglobin	J:211773
	decreased prepulse inhibition	J:211773
	increased circulating potassium level	J:211773
Ercc3^{tm1b(NCOM)Mfgc}/Ercc3^{tm1b(NCOM)Mfgc} C57BL/6N-Ercc3^{tm1b(NCOM)Mfgc}/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Ercc3^tm1Jhjh/Ercc3^tm1Jhjh B6.129P2-Ercc3^tm1Jhjh	embryonic lethality between somite formation and embryo turning, complete penetrance	J:145759
Ercc3^tm2Jhjh/Ercc3^tm2Jhjh B6.129P2-Ercc3^tm2Jhjh	acanthosis	J:145759
	epidermal hyperplasia	J:145759
	increased cellular sensitivity to gamma-irradiation	J:145759
	increased cellular sensitivity to ultraviolet irradiation	J:145759
	normal mortality/aging	J:145759

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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