Ets1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ets1
E26 avian leukemia oncogene 1, 5' domain
MGI:95455

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ets1^tm1Jml/Ets1^tm1Jml Ets2^tm2Rgo/Ets2^tm2Rgo involves: 129S/SvEv * C57BL/6 * FVB/N	abnormal vascular branching morphogenesis	J:151187
	dilated vasculature	J:151187
	edema	J:151187
	normal embryo phenotype	J:151187
	embryonic lethality during organogenesis, incomplete penetrance	J:151187
	hemorrhage	J:151187
	increased vascular endothelial cell apoptosis	J:151187
	lethality throughout fetal growth and development, complete penetrance	J:151187
Ets1^tm1Jml/Ets1^tm1Jml Ets2^tm5.1Rgo/Ets2^tm5.1Rgo Meox2^tm1(cre)Sor/Meox2⁺ involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * FVB/N	edema	J:151187
	hemorrhage	J:151187
	prenatal lethality, complete penetrance	J:151187
Ets1^tm1Jml/Ets1^tm1Jml Ets2^tm5.1Rgo/Ets2^tm5.1Rgo Tg(Tek-cre)1Ywa/0 involves: 129S/SvEv * C57BL/6 * FVB/N	abnormal vascular branching morphogenesis	J:151187
	embryonic lethality, complete penetrance	J:151187
	increased vascular endothelial cell apoptosis	J:151187
Ets1^tm1Jml/Ets1^tm1Jml Tg(TcraH-Y,TcrbH-Y)71Vbo/0 involves: 129S/SvEv * C57BL/6 * C57BL/6J * DBA/2J	decreased CD8-positive, alpha-beta T cell number	J:125056
	normal immune system phenotype	J:125056
	increased double-negative T cell number	J:125056
Ets1^tm2Jml/Ets1^tm2Jml Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ Pax3^tm1(cre)Joe/Pax3⁺ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * C57BL/6NCrl	abnormal cardiac neural crest cell migration	J:334073
	abnormal cardiac outflow tract development	J:334073
	abnormal conotruncal ridge morphology	J:334073
	abnormal neural crest cell physiology	J:334073
	double outlet right ventricle	J:334073

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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