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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zfp521
zinc finger protein 521
MGI:95459
49 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tg(Emu-Zfp521)1Homy/0
Not Specified 		abnormal B cell differentiation J:160392
normal hematopoietic system phenotype J:160392
increased B cell number J:160392
normal neoplasm J:160392
Zfp521tm1Ngc/Zfp521tm1Ngc
Tg(Col2a1-cre)#Amc/0
Not Specified 		abnormal bone mineralization J:166058
abnormal bone structure J:166058
abnormal chondrocyte physiology J:166058, J:175572
abnormal long bone epiphyseal plate morphology J:166058
abnormal long bone epiphyseal plate proliferative zone J:166058
decreased length of long bones J:166058, J:175572
decreased long bone epiphyseal plate size J:166058
decreased width of hypertrophic chondrocyte zone J:166058
postnatal growth retardation J:166058, J:175572
proportional dwarf J:166058
small thoracic cage J:166058
small vertebrae J:166058
Zfp521tm1Nohk/Zfp521+
involves: C57BL/6J 		no abnormal phenotype detected J:214267
Zfp521tm1Nohk/Zfp521tm1Nohk
B6J.Cg-Zfp521tm1Nohk 		abnormal cerebellum morphology J:214267
abnormal dentate gyrus morphology J:214267
abnormal hippocampus development J:214267
abnormal hippocampus granule cell morphology J:214267
abnormal hippocampus morphology J:214267
abnormal hippocampus neuron morphology J:214267
abnormal impulsive behavior control J:214267
abnormal learning/memory/conditioning J:214267
abnormal neuronal stem cell physiology J:214267
abnormal resting posture J:214267
abnormal social investigation J:214267
decreased adrenal gland weight J:214267
decreased anxiety-related response J:214267
decreased body size J:214267
decreased body weight J:214267
decreased brain size J:214267
decreased brain weight J:214267
decreased heart weight J:214267
decreased kidney weight J:214267
decreased liver weight J:214267
decreased long bone epiphyseal plate size J:214267
decreased lung weight J:214267
decreased neuronal precursor cell number J:214267
decreased pituitary gland weight J:214267
decreased prepulse inhibition J:214267
decreased spleen weight J:214267
decreased thymus weight J:214267
impaired neuron differentiation J:214267
increased coping response J:214267
increased locomotor activity J:214267
postnatal growth retardation J:214267
premature death J:214267
Zfp521tm2Ngc/Zfp521+
Not Specified 		abnormal clavicle morphology J:167992
increased hyoid bone size J:167992
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory