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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fancc
Fanconi anemia, complementation group C
MGI:95480
34 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fancctm1Mab/Fancctm1Mab
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased telomere length J:157096
Fancctm1Mab/Fancctm1Mab
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal common lymphocyte progenitor cell morphology J:71134
abnormal fertility/fecundity J:32080
abnormal hematopoietic stem cell physiology J:47897
abnormal hematopoietic system physiology J:47897
abnormal ovary morphology J:32080
abnormal reproductive system morphology J:32080
absent corpus luteum J:32080
arrest of spermatogenesis J:32080
decreased common myeloid progenitor cell number J:71134
decreased litter size J:32080
female infertility J:32080
normal hematopoietic system phenotype J:32080
impaired ovarian folliculogenesis J:32080
increased cellular sensitivity to methylmethanesulfonate J:47897
male infertility J:32080
reduced fertility J:32080
seminiferous tubule degeneration J:32080
testicular atrophy J:32080
thrombocytopenia J:71134
Fancctm1Mgo/Fancctm1Mgo
involves: 129S4/SvJaeSor * C57BL/6 		abnormal cell cycle checkpoint function J:61512
abnormal seminiferous tubule morphology J:61512
absent common myeloid progenitor cells J:61512
absent ovarian follicles J:61512
decreased germ cell number J:61512
decreased litter size J:61512
decreased oocyte number J:61512
decreased testis weight J:61512
induced chromosome breakage J:61512
oligozoospermia J:61512
ovary hypoplasia J:61512
reduced female fertility J:61512
small ovary J:61512
spontaneous chromosome breakage J:61512
uterus hypoplasia J:61512
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory