Fcer2a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fcer2a
Fc receptor, IgE, low affinity II, alpha polypeptide
MGI:95497

17 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fcer2a^Hie/Fcer2a^Hie NZB	increased IgE level	J:93999
Fcer2a^tm1Kik/Fcer2a^tm1Kik involves: 129P2/OlaHsd * C57BL/6	abnormal cytokine secretion	J:129296
	abnormal humoral immune response	J:19437
	abnormal immune system physiology	J:129296
	increased immunoglobulin level	J:129296
Fcer2a^tm1Max/Fcer2a^tm1Max involves: C57BL/6	abnormal intestinal absorption	J:107857
	abnormal macrophage chemotaxis	J:57738
	decreased IgG1 level	J:18952
	decreased IgG2b level	J:18952
	impaired eosinophil recruitment	J:57738
	increased IgE level	J:18952, J:57738, J:107857
	increased IgM level	J:18952
	increased susceptibility to type I hypersensitivity reaction	J:57738
Fcer2a^tm1Max/Fcer2a^tm1Max involves: C57BL/6J	decreased body temperature	J:198154
Fcer2a^tm1Putt/Fcer2a⁺ involves: 129S/SvEv * C57BL/6	increased IgE level	J:69547
Fcer2a^tm1Putt/Fcer2a^tm1Putt involves: 129S/SvEv * C57BL/6	abnormal B cell proliferation	J:69547
Tg(Thy1-Fcer2a)2431Putt/? involves: BALB/c * C57BL/6	abnormal immune system physiology	J:129296
	decreased IgE level	J:20421
	decreased IgG1 level	J:20421
	increased eosinophil cell number	J:20421
Tg(Thy1-Fcer2a)2733Putt/? involves: BALB/c * C57BL/6	normal immune system phenotype	J:20421

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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