Fcgr1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fcgr1
Fc receptor, IgG, high affinity I
MGI:95498

5 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Del(1Fcgr2b-Fcgr3)1Rav/Del(1Fcgr2b-Fcgr3)1Rav Fcgr1^tm1Hoga/Fcgr1^tm1Hoga Tg(FCGR1A)#Jgjw/0 Tg(FCGR2A)11Mkz/0 Tg(FCGR2B)#Rav/0 Tg(FCGR3A)1156Rav/0 Tg(FCGR3B)1373Rav/0 involves: 129S1/Sv * C57BL/6 * CBA/Ca * FVB/N	no abnormal phenotype detected	J:183615
Fcer1a^tm1Knt/Fcer1a^tm1Knt Fcer2a^tm1Max/Fcer2a^tm1Max Fcgr1^tm1Jsv/Fcgr1^tm1Jsv Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk Fcgr3^tm1Jsv/Fcgr3^tm1Jsv B6.Cg-Fcgr2b^tm1Ttk Fcgr3^tm1Jsv Fcer1a^tm1Knt Fcgr1^tm1Jsv Fcer2a^tm1Max	abnormal macrophage physiology	J:144620
	abnormal mast cell physiology	J:144620
	increased susceptibility to type I hypersensitivity reaction	J:144620
Fcgr1^tm1Jsv/Fcgr1^tm1Jsv Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk Fcgr3^tm1Jsv/Fcgr3^tm1Jsv involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6	impaired macrophage phagocytosis	J:83995

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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