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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fcgr2b
Fc receptor, IgG, low affinity IIb
MGI:95499
41 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fcgr2btm1.1Jsv/Fcgr2btm1.1Jsv
involves: C57BL/6 * FVB/N 		no abnormal phenotype detected J:179175
Fcgr2btm1.2Rav/Fcgr2btm1.2Rav
involves: C57BL/6 		normal skeleton phenotype J:197378
Fcgr2btm1Kgcs/Fcgr2b+
involves: C57BL/6 		decreased B cell apoptosis J:190890
increased anti-chromatin antibody level J:190890
increased anti-double stranded DNA antibody level J:190890
increased germinal center B cell number J:190890
increased IgG1 level J:190890
increased IgG3 level J:190890
increased IgM level J:190890
increased susceptibility to induced arthritis J:190890
renal glomerular protein deposits J:190890
Fcgr2btm1Ttk/Fcgr2btm1Ttk
B6.129S4-Fcgr2btm1Ttk 		abnormal hypersensitivity reaction J:64152
abnormal seizure response to electrical stimulation J:169028
anemia J:64152
decreased body weight J:64152
dehydration J:64152
edema J:64152
enlarged lymph nodes J:64152
enlarged spleen J:64152
glomerulonephritis J:64152
hunched posture J:64152
increased immunoglobulin level J:64152
increased inflammatory response J:64152
increased urine protein level J:64152
kidney inflammation J:64152
liver inflammation J:64152
lung inflammation J:64152
maximal tonic hindlimb extension seizures J:169028
pancreas inflammation J:64152
premature death J:64152
salivary gland inflammation J:64152
tonic-clonic seizures J:169028
vascular inflammation J:64152
Fcgr2btm1Ttk/Fcgr2btm1Ttk
C.129S4-Fcgr2btm1Ttk 		decreased susceptibility to parasitic infection J:120905
normal mortality/aging J:64152
Fcgr2btm1Ttk/Fcgr2btm1Ttk
involves: 129S4/SvJae 		abnormal mast cell physiology J:31133
increased IgA level J:31133
increased IgG1 level J:31133
increased IgG2a level J:31133
increased IgG2b level J:31133
increased IgG3 level J:31133
increased IgG level J:31133
increased IgM level J:31133
increased susceptibility to type I hypersensitivity reaction J:31133
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Not Specified 		increased susceptibility to induced arthritis J:106191
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory