Fcgr3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fcgr3
Fc receptor, IgG, low affinity III
MGI:95500

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fcer1a^tm1Knt/Fcer1a^tm1Knt Fcer2a^tm1Max/Fcer2a^tm1Max Fcgr1^tm1Jsv/Fcgr1^tm1Jsv Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk Fcgr3^tm1Jsv/Fcgr3^tm1Jsv B6.Cg-Fcgr2b^tm1Ttk Fcgr3^tm1Jsv Fcer1a^tm1Knt Fcgr1^tm1Jsv Fcer2a^tm1Max	abnormal macrophage physiology	J:144620
	abnormal mast cell physiology	J:144620
	increased susceptibility to type I hypersensitivity reaction	J:144620
Fcgr1^tm1Jsv/Fcgr1^tm1Jsv Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk Fcgr3^tm1Jsv/Fcgr3^tm1Jsv involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6	impaired macrophage phagocytosis	J:83995
Fcgr3^tm1Jsv/Fcgr3^tm1Jsv Sle21^129P2/Ola/Sle21^129P2/Ola B6.129P2-Fcgr3^tm1Jsv	enlarged spleen	J:179175
	increased activated T cell number	J:179175
	increased anti-chromatin antibody level	J:179175
	increased anti-double stranded DNA antibody level	J:179175
	increased anti-histone antibody level	J:179175
	increased anti-single stranded DNA antibody level	J:179175
	increased B cell number	J:179175
	increased spleen weight	J:179175
	normal mortality/aging	J:179175

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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