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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fes
feline sarcoma oncogene
MGI:95514
43 phenotypes from 4 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Festm1Mcs/Festm1Mcs
involves: 129X1/SvJ 		abnormal bone marrow cell morphology/development J:64748
abnormal leukocyte cell number J:64748
abnormal macrophage physiology J:64748
abnormal megakaryocyte progenitor cell morphology J:64748
conjunctivitis J:64748
decreased B cell number J:64748
decreased bone marrow cell number J:64748
increased granulocyte number J:64748
increased monocyte cell number J:64748
increased neutrophil cell number J:64748
increased susceptibility to bacterial infection J:64748
lethality throughout fetal growth and development, incomplete penetrance J:64748
postnatal growth retardation J:64748
skin lesions J:64748
thymus hypoplasia J:64748
Festm1Pag/Festm1Pag
involves: 129S1/Sv * 129X1/SvJ * CD-1 		normal hematopoietic system phenotype J:84535
no abnormal phenotype detected J:84535
Festm2Mcs/Fes+
chimera involves: 129X1/SvJ * C57BL/6 		abnormal frontal lobe morphology J:76509
abnormal heart morphology J:76509
abnormal myocardial trabeculae morphology J:76509
dilated heart ventricle J:76509
distended abdomen J:76509
down-turned corners of mouth J:76509
downturned snout J:76509
enlarged heart J:76509
enlarged lateral ventricles J:76509
gastrointestinal hemorrhage J:76509
hemorrhage J:76509
hydrops fetalis J:76509
increased fetal weight J:76509
lethality throughout fetal growth and development, complete penetrance J:76509
liver hemorrhage J:76509
thin myocardium compact layer J:76509
ventricular septal defect J:76509
Festm2Mcs/Festm2Mcs
chimera involves: 129X1/SvJ * C57BL/6 		abnormal vasculogenesis J:76509
lethality throughout fetal growth and development, complete penetrance J:76509
Festm2Pag/Festm2Pag
involves: 129S1/Sv * 129X1/SvJ * CD-1 		abnormal myelopoiesis J:98590
decreased B cell number J:98590
increased erythrocyte cell number J:98590
increased hematocrit J:98590
increased hemoglobin content J:98590
increased litter size J:98590
increased pre-B cell number J:98590
increased pro-B cell number J:98590
increased susceptibility to endotoxin shock J:98590
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory