Fgf2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgf2
fibroblast growth factor 2
MGI:95516

45 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgf2^{tm1b(EUCOMM)Wtsi}/Fgf2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Fgf2^{tm1b(EUCOMM)Wtsi}/H	abnormal retina morphology	J:211773
	increased circulating serum albumin level	J:211773
	increased circulating total protein level	J:211773
	limb grasping	J:211773
Fgf2^tm1Bas/Fgf2^tm1Bas involves: 129/Sv * 129P2/OlaHsd * C57BL/6	loss of glutamate neurons	J:126973
Fgf2^tm1Bas/Fgf2^tm1Bas involves: 129P2/OlaHsd * C57BL/6	abnormal frontal lobe morphology	J:47664
	abnormal myeloblast morphology/development	J:60597
	abnormal stratification in cerebral cortex	J:47664
	delayed wound healing	J:47664
	normal hearing/vestibular/ear phenotype	J:104949
	thickened cerebral cortex	J:47664
Fgf2^tm1Bee/Fgf2^tm1Bee B6.129P2-Fgf2^tm1Bee	normal vision/eye phenotype	J:75629
Fgf2^tm1Doe/Fgf2^tm1Doe B6.129P2-Fgf2^tm1Doe	abnormal vascular endothelial cell migration	J:114567
Fgf2^tm1Doe/Fgf2^tm1Doe involves: 129P2/OlaHsd * Black Swiss	abnormal cardiac muscle relaxation	J:119652
	abnormal cerebral cortex pyramidal cell morphology	J:126973
	abnormal common myeloid progenitor cell morphology	J:45775
	abnormal neuron differentiation	J:126024
	abnormal neuron morphology	J:126973
	abnormal sleep duration	J:126973
	decreased cardiac muscle contractility	J:119652
	decreased cerebral cortex pyramidal cell number	J:126973
	decreased left ventricle developed pressure	J:45775
	decreased left ventricle systolic pressure	J:119652
	decreased mean systemic arterial blood pressure	J:45775
	decreased vasoconstriction	J:45775
	increased cardiomyocyte apoptosis	J:119652
	loss of glutamate neurons	J:126973
	thrombocytosis	J:45775
Fgf2^tm1Doe/Fgf2^tm1Doe involves: 129P2/OlaHsd * C57BL/6	abnormal response to cardiac infarction	J:126804
Fgf2^tm1Doe/Fgf2^tm1Doe involves: 129P2/OlaHsd * C57BL/6	increased myocardial infarct size	J:126804
Fgf2^tm1Zllr/Fgf2^tm1Zllr involves: 129S1/Sv * 129X1/SvJ	normal muscle phenotype	J:85088
Fgf2^tm1Zllr/Fgf2^tm1Zllr involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal baroreceptor physiology	J:49141
	abnormal cerebral cortex morphology	J:49141
	abnormal hippocampal commissure morphology	J:49141
	abnormal neuronal migration	J:49141
	abnormal spinal cord grey matter morphology	J:49141
	abnormal stratification in cerebral cortex	J:49141
	normal behavior/neurological phenotype	J:49141
	decreased cerebral cortex pyramidal cell number	J:49141
	normal hearing/vestibular/ear phenotype	J:104949
	hypotension	J:49141
	loss of cortex neurons	J:49141
	thin cerebral cortex	J:49141
Fgf2^tm2Doe/Fgf2^tm2Doe involves: 129P2/OlaHsd * Black Swiss	abnormal bone marrow morphology	J:147213
	abnormal cardiac muscle relaxation	J:119652
	decreased bone mineral content	J:147213
	decreased bone mineral density of vertebrae	J:147213
	decreased cardiac muscle contractility	J:119652
	decreased left ventricle systolic pressure	J:119652
	increased cardiomyocyte apoptosis	J:119652
Fgf2^tm3Doe/Fgf2^tm3Doe involves: 129P2/OlaHsd * Black Swiss	normal cardiovascular system phenotype	J:144353
	normal mortality/aging	J:144353
	normal reproductive system phenotype	J:144353

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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