Fgf4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgf4
fibroblast growth factor 4
MGI:95518

24 phenotypes from 9 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgf4^em1(IMPC)H/Fgf4⁺ C57BL/6NTac-Fgf4^em1(IMPC)H/H	decreased grip strength	J:211773
Fgf4^em1(IMPC)H/Fgf4^em1(IMPC)H C57BL/6NTac-Fgf4^em1(IMPC)H/H	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Fgf4^tm1.1Mrt/Fgf4^tm1.1Mrt involves: 129P2/OlaHsd	embryonic lethality between implantation and somite formation, complete penetrance	J:61886
Fgf4^tm1.2Mrt/Fgf4^tm1.2Mrt Tg(Sftpc-cre)1Blh/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * ICR	normal respiratory system phenotype	J:106392
Fgf4^tm1.2Mrt/Fgf4^tm1.3Mrt Tg(Msx2-cre)5Rem/0 involves: 129P2/OlaHsd	no abnormal phenotype detected	J:61886
Fgf4^tm1Gol/Fgf4^tm1Gol involves: C57BL/6J	abnormal embryo development	J:22275
	abnormal extraembryonic endoderm formation	J:22275
	decreased egg cylinder size	J:22275
	decreased inner cell mass proliferation	J:22275
	embryonic growth arrest	J:22275
	embryonic lethality between implantation and somite formation, complete penetrance	J:22275
	empty decidua capsularis	J:22275
Fgf4^tm1Mrc/Fgf4^tm1.1Mrc Tg(Rarb-cre)1Mrc/0 involves: 129S1/Sv * 129X1/SvJ	normal limbs/digits/tail phenotype	J:60091
Fgf4^tm1Mrc/Fgf4^tm1Mrc involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:60091
Fgf4^tm1Mrc/Fgf4^tm2Mrc Tg(Rarb-cre)1Mrc/0 involves: 129S1/Sv * 129X1/SvJ	normal limbs/digits/tail phenotype	J:60091
	normal skeleton phenotype	J:60091
Fgf4^tm2Mrc/Fgf4^tm2Mrc involves: 129S1/Sv * 129X1/SvJ	prenatal lethality	J:60091
Tg(CAG-Bgeo,-Fgf4)1Mrt/? Tg(Msx2-cre)5Rem/? involves: 129P2/OlaHsd	abnormal calcaneum morphology	J:104411
	abnormal digit development	J:104411
	abnormal limb development	J:104411
	abnormal reproductive system morphology	J:104411
	broad limb buds	J:104411
	eyelid hyperplasia	J:104411
	fused tarsal bones	J:104411
	polysyndactyly	J:104411
	postnatal growth retardation	J:104411

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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