Fgf7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgf7
fibroblast growth factor 7
MGI:95521

34 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgf7^{tm1e.1(EUCOMM)Hmgu}/Fgf7^{tm1e.1(EUCOMM)Hmgu} C57BL/6N-Fgf7^{tm1e.1(EUCOMM)Hmgu}/H	abnormal iris morphology	J:211773
	abnormal placement of pupils	J:211773
	abnormal startle reflex	J:211773
	abnormal tail length	J:211773
	impaired pupillary reflex	J:211773
	impaired righting response	J:211773
	irregularly shaped pupil	J:211773
	mydriasis	J:211773
Fgf7^tm1Efu/Fgf7^tm1Efu B6.129-Fgf7^tm1Efu	increased susceptibility to pharmacologically induced seizures	J:161954
Fgf7^tm1Efu/Fgf7^tm1Efu involves: 129S1/Sv * 129X1/SvJ	abnormal synaptic vesicle clustering	J:161954
	abnormal synaptic vesicle morphology	J:161954
	abnormal synaptic vesicle number	J:161954
	decreased miniature inhibitory postsynaptic current frequency	J:161954
Fgf7^tm1Efu/Fgf7^tm1Efu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal coat appearance	J:31155
	abnormal immune system physiology	J:129368
	abnormal kidney collecting duct epithelium morphology	J:53739
	abnormal kidney development	J:53739
	abnormal kidney inner medulla morphology	J:53739
	abnormal papillary duct morphology	J:53739
	abnormal response to transplant	J:129368
	decreased nephron number	J:53739
	disheveled coat	J:31155
	greasy coat	J:31155
	normal hematopoietic system phenotype	J:129368
	normal homeostasis/metabolism phenotype	J:31155
	normal immune system phenotype	J:129368
	impaired branching involved in ureteric bud morphogenesis	J:53739
	normal integument phenotype	J:31155
	kidney cortex hypoplasia	J:53739
	kidney papillary hypoplasia	J:53739
	matted coat	J:31155
	normal reproductive system phenotype	J:31155
	small kidney	J:53739
	spleen hypoplasia	J:129368

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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