Fh1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fh1
fumarate hydratase 1
MGI:95530

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fh1^tm1.1Pjp/Fh1^tm1.1Pjp involves: 129X1/SvJ * BALB/c * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:120969
Fh1^tm1Pjp/Fh1^tm1Pjp Tg(Cdh16-cre)91Igr/0 involves: 129X1/SvJ * ICR	abnormal enzyme/coenzyme activity	J:120969
	abnormal fibroblast physiology	J:198486
	abnormal renal tubule epithelium morphology	J:120969
	abnormal tricarboxylic acid cycle	J:198486
	abnormal urine homeostasis	J:198486
	enlarged kidney	J:198486
	glomerulosclerosis	J:120969
	hydronephrosis	J:120969
	kidney corticomedullary cyst	J:120969
	kidney cyst	J:120969, J:198486
	kidney failure	J:120969
	polyuria	J:120969

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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