Fh1 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fh1
fumarate hydratase 1
MGI:95530

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fh1^tm1.1Pjp/Fh1^tm1.1Pjp involves: 129X1/SvJ * BALB/c * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:120969
Fh1^tm1Pjp/Fh1^tm1Pjp Tg(Cdh16-cre)91Igr/0 involves: 129X1/SvJ * ICR	abnormal enzyme/coenzyme activity	J:120969
	abnormal fibroblast physiology	J:198486
	abnormal renal tubule epithelium morphology	J:120969
	abnormal tricarboxylic acid cycle	J:198486
	abnormal urine homeostasis	J:198486
	enlarged kidney	J:198486
	glomerulosclerosis	J:120969
	hydronephrosis	J:120969
	kidney corticomedullary cyst	J:120969
	kidney cyst	J:120969, J:198486
	kidney failure	J:120969
	polyuria	J:120969

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24