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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fkbp4
FK506 binding protein 4
MGI:95543
61 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fkbp4em1(IMPC)Mbp/Fkbp4+
C57BL/6N-Fkbp4em1(IMPC)Mbp/MbpMmucd 		abnormal placenta morphology J:211773
no spontaneous movement J:211773
Fkbp4em1(IMPC)Mbp/Fkbp4em1(IMPC)Mbp
C57BL/6N-Fkbp4em1(IMPC)Mbp/MbpMmucd 		abnormal body wall morphology J:211773
abnormal cholesterol homeostasis J:211773
abnormal lymph node morphology J:211773
abnormal male genitalia morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
abnormal vitreous body morphology J:211773
absent testes J:211773
cataract J:211773
decreased heart rate J:211773
decreased mean corpuscular volume J:211773
enlarged epididymis J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
female infertility J:211773
male infertility J:211773
no spontaneous movement J:211773
preweaning lethality, incomplete penetrance J:211773
prolonged RR interval J:211773
small epididymis J:211773
small kidney J:211773
small seminal vesicle J:211773
small testis J:211773
Fkbp4tm1Dvds/Fkbp4tm1Dvds
either: (involves: CD-1) or (involves: 129X1/SvJ * C57BL/6) 		hairpin sperm flagellum J:118360
impaired fertilization J:118360
male infertility J:118360
oligozoospermia J:118360
Fkbp4tm1Dvds/Fkbp4tm1Dvds
involves: 129X1/SvJ * C57BL/6 		abnormal luminal closure J:101405
abnormal prostate gland morphology J:98554
abnormal reproductive system physiology J:98554
abnormal secondary sex determination J:98554
abnormal seminal vesicle morphology J:98554
abnormal testis morphology J:98554
abnormal uterine receptivity J:101405
absent prostate gland anterior lobe J:98554
ambiguous external male genitalia J:98554
asthenozoospermia J:98554
failure of embryo implantation J:101405
female infertility J:101405
hypospadia J:98554
impaired fertilization J:98554, J:101405
male infertility J:98554, J:101405
male pseudohermaphroditism J:98554
prenatal lethality, incomplete penetrance J:98554
small prostate gland anterior lobe J:98554
small seminal vesicle J:98554
unilateral cryptorchism J:98554
Fkbp4tm1Shou/Fkbp4tm1Shou
either: (involves: 129S/SvEv) or (involves: 129S/SvEv * C57BL/6J) 		abnormal decidualization J:114715
abnormal mammary gland development J:114715
decreased superovulation rate J:114715
female infertility J:114715
Fkbp4tm1Shou/Fkbp4tm1Shou
involves: 129S/SvEv 		abnormal anogenital distance J:120960
abnormal foreskin morphology J:120960
abnormal male reproductive system morphology J:120960
abnormal penis morphology J:120960
abnormal prostate gland development J:120960
abnormal reproductive system morphology J:120960
abnormal reproductive system physiology J:120960
abnormal sperm motility J:120960
decreased body weight J:120960
decreased litter size J:120960
decreased seminal vesicle weight J:120960
female infertility J:120960
increased circulating testosterone level J:120960
penile hypospadia J:120960
postnatal growth retardation J:120960
reduced male fertility J:120960
small penis J:120960
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory