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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Flnc
filamin C, gamma
MGI:95557
35 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Flncem1(IMPC)Bay/Flnc+
C57BL/6N-Flncem1(IMPC)Bay/BayMmucd 		decreased body temperature J:211773
Flncem1(IMPC)Bay/Flncem1(IMPC)Bay
C57BL/6N-Flncem1(IMPC)Bay/BayMmucd 		abnormal heart looping J:211773
abnormal heart morphology J:211773
abnormal somite shape J:211773
abnormal vitelline vasculature morphology J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Flnctm1.1Rsdf/Flnc+
involves: C57BL/6 		abnormal muscle fiber morphology J:226976
abnormal sarcomere morphology J:226976
abnormal Z line morphology J:226976
decreased food intake J:226976
decreased grip strength J:226976
decreased locomotor activity J:226976
decreased respiratory quotient J:226976
decreased vertical activity J:226976
normal muscle phenotype J:226976
skeletal muscle fiber degeneration J:226976
Flnctm1.1Rsdf/Flnctm1.1Rsdf
involves: C57BL/6 		normal mortality/aging J:226976
Flnctm1Lmk/Flnctm1Lmk
involves: 129X1/SvJ * C57BL/6 		abnormal diaphragm morphology J:112170
abnormal extensor digitorum longus morphology J:112170
abnormal intercostal muscle morphology J:112170
abnormal myogenesis J:112170
abnormal skeletal muscle fiber morphology J:112170
abnormal skeletal muscle morphology J:112170
abnormal soleus morphology J:112170
abnormal tibialis anterior morphology J:112170
normal cardiovascular system phenotype J:112170
centrally nucleated skeletal muscle fibers J:112170
decreased fetal size J:112170
decreased skeletal muscle fiber number J:112170
decreased skeletal muscle mass J:112170
hyporesponsive to tactile stimuli J:112170
increased variability of skeletal muscle fiber size J:112170
neonatal lethality, complete penetrance J:112170
respiratory failure J:112170
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory