Flt1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Flt1
FMS-like tyrosine kinase 1
MGI:95558

17 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Akt1^tm1Mbb/Akt1⁺ Flt1^tm1Jrt/Flt1⁺ involves: 129P2/OlaHsd	normal cardiovascular system phenotype	J:151369
Dmd^mdx-5Cv/Dmd^mdx-5Cv Flt1^tm1Jrt/Flt1⁺ involves: C3HA * C57BL/6Ros	abnormal blood circulation	J:164891
	abnormal muscle contractility	J:164891
	abnormal muscle development	J:164891
	abnormal skeletal muscle fiber morphology	J:164891
	abnormal skeletal muscle fiber size	J:164891
	increased capillary density	J:164891
	increased satellite cell number	J:164891
	normal muscle phenotype	J:164891
Dmd^mdx-5Cv/Dmd^mdx-5Cv Flt1^tm1Jrt/Flt1⁺ Utrn^tm1Jrs/Utrn^tm1Jrs involves: 129S1/Sv * 129X1/SvJ * C3HA * C57BL/6Ros	centrally nucleated skeletal muscle fibers	J:164891
	extended life span	J:164891
	increased body weight	J:164891
Flt1^tm1.1Fong/Flt1^tm1.1Fong Kdr^tm1Jrt/Kdr⁺ Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/Gt(ROSA)26Sor⁺ involves: 129 * C57BL/6NCr * CD-1	increased angiogenesis	J:202202
Flt1^tm2Msh/Flt1^tm2Msh Kdr^tm1Jrt/Kdr⁺ involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal vascular endothelial cell differentiation	J:95387
	abnormal vascular endothelial cell migration	J:95387
	prenatal lethality, incomplete penetrance	J:95387
Flt1^tm2Msh/Flt1^tm2Msh Kdr^tm1Jrt/Kdr^tm1Jrt involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal vascular endothelial cell migration	J:95387
	prenatal lethality	J:95387

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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