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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Flt3
FMS-like tyrosine kinase 3
MGI:95559
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Col1a1tm2(tetO-IDH2*R140Q)Ppp/Col1a1tm2(tetO-IDH2*R140Q)Ppp
Flt3tm1.1Dosm/Flt3tm1.1Dosm
Gt(ROSA)26Sortm1(rtTA*M2)Jae/?
involves: 129 * C57BL/6 		increased leukemia incidence J:210097
premature death J:210097
Flt3tm1Dgg/Flt3+
Kmt2atm1Clgr/Kmt2a+
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J 		anemia J:189096
enlarged spleen J:189096
increased erythroblast number J:189096
increased leukemia incidence J:189096
increased leukocyte cell number J:189096
premature death J:189096
thrombocytopenia J:189096
Flt3tm1Dgg/Flt3tm1Dgg
Kmt2atm1Clgr/Kmt2a+
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J 		enlarged spleen J:189096
increased leukemia incidence J:189096
increased leukocyte cell number J:189096
premature death J:189096
Flt3tm1Irl/Flt3tm1Irl
KitW/KitW-v
involves: 129S/SvEv * C57BL/6 		abnormal blood cell morphology/development J:27238
abnormal common myeloid progenitor cell morphology J:27238
abnormal leukocyte morphology J:27238
abnormal myelopoiesis J:27238
abnormal T cell number J:27238
decreased B cell number J:27238
decreased body weight J:27238
decreased bone marrow cell number J:27238
decreased double-negative T cell number J:27238
decreased double-positive T cell number J:27238
decreased lymphocyte cell number J:27238
decreased pre-B cell number J:27238
decreased pro-B cell number J:27238
thymus hypoplasia J:27238
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory