Flt4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Flt4
FMS-like tyrosine kinase 4
MGI:95561

30 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Flt4^Chy/Flt4⁺ involves: C3H	abnormal adipose tissue distribution	J:72387
	abnormal intestine morphology	J:72387
	abnormal liver morphology	J:72387
	abnormal lymph circulation	J:72387
	abnormal lymphangiogenesis	J:177405
	abnormal lymphatic vessel morphology	J:72387
	chylous ascites	J:13981, J:72387
	edema	J:177405
	extremity edema	J:13981
	lymphedema	J:72387
	postnatal lethality	J:72387
	normal reproductive system phenotype	J:13981
	thick dermal layer	J:72387
Flt4^Chy/Flt4^Chy involves: C3H	abnormal lymphangiogenesis	J:177405
	absent lymphatic vessels	J:177405
	normal cardiovascular system phenotype	J:177405
	edema	J:177405
Flt4^Chy/Flt4^tm1Ali involves: C3H	embryonic growth retardation	J:72387
Flt4^Chy/Flt4^tm1Ali involves: C3H	prenatal lethality, complete penetrance	J:72387
Flt4^tm1.1Ichi/Flt4⁺ B6.Cg-Flt4^tm1.1Ichi	chylous ascites	J:159024
Flt4^tm1.2Yhe/Flt4^tm1.2Yhe involves: 129/Sv * C57BL/6J * FVB/N	abnormal lymphangiogenesis	J:177405
	absent lymphatic vessels	J:177405
	normal cardiovascular system phenotype	J:177405
	edema	J:177405
Flt4^tm1Ali/Flt4^tm1Ali Not Specified	abnormal anterior cardinal vein morphology	J:50761
	abnormal dorsal aorta morphology	J:50761
	abnormal perineural vascular plexus morphology	J:50761
	abnormal vascular development	J:50761
	abnormal vitelline vascular remodeling	J:50761
	embryonic growth retardation	J:50761
	embryonic lethality during organogenesis, complete penetrance	J:50761, J:137909
	hemopericardium	J:50761
	pale yolk sac	J:50761
	pericardial edema	J:50761
Flt4^tm1Ali/Flt4^tm2.1Ali Krt19^tm1(cre)Mmt/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL	abnormal blood vessel morphology	J:137909
	embryonic lethality during organogenesis, complete penetrance	J:137909
Flt4^tm1Ali/Flt4^tm2Ali involves: 129S1/Sv * 129X1/SvJ * ICR	absent lymphatic vessels	J:137909
Flt4^tm2.1Ali/Flt4^tm2.1Ali involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL	no abnormal phenotype detected	J:137909
Flt4^tm2Ali/Flt4⁺ involves: 129S1/Sv * 129X1/SvJ * ICR	abnormal lymph circulation	J:137909
	abnormal lymphatic vessel morphology	J:137909
	chylous ascites	J:137909
	hydrops fetalis	J:137909
Flt4^tm2Ali/Flt4^tm2Ali involves: 129S1/Sv * 129X1/SvJ * ICR	absent lymphatic vessels	J:137909
	hydrops fetalis	J:137909
	neonatal lethality, complete penetrance	J:137909

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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