Fos Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fos
FBJ osteosarcoma oncogene
MGI:95574

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Col1a1^{tm1(tetO-Fos)Wag}/Col1a1⁺ Rag1^tm1Mom/Rag1^tm1Mom Tg(KRT5-rtTA)T2D6Sgkd/0 involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N	normal integument phenotype	J:201145
	skin hyperplasia	J:201145
	skin lesions	J:201145
Col1a1^{tm1(tetO-Fos)Wag}/Col1a1⁺ Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/Gt(ROSA)26Sor⁺ Tg(Alb1-cre)7Gsc/0 involves: 129 * C57BL/6 * FVB/N	abnormal liver morphology	J:210545
	premature death	J:210545
Col1a1^{tm5(tetO-Jun/Fos)Wag}/Col1a1⁺ Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/Gt(ROSA)26Sor⁺ Tg(Alb1-cre)7Gsc/0 involves: 129 * C57BL/6 * FVB/N	abnormal liver morphology	J:210545
	premature death	J:210545
Egfr^wa2/Egfr⁺ Fos^{tm2(Fosl1)Wag}/Fos^{tm2(Fosl1)Wag} Tg(KRT5-SOS1)892A6Wag/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	decreased tumor growth/size	J:175064
	increased skin papilloma incidence	J:175064
Egfr^wa2/Egfr⁺ Fos^tm3.1Wag/Fos^tm3.1Wag Tg(KRT5-SOS1)892A6Wag/0 involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL	decreased tumor growth/size	J:175064
	increased skin papilloma incidence	J:175064
Egfr^wa2/Egfr⁺ Fos^tm4.1Wag/Fos^tm4.1Wag Tg(KRT5-SOS1)892A6Wag/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	increased skin papilloma incidence	J:175064
Egfr^wa2/Egfr⁺ Fos^tm5.1Wag/Fos^tm5.1Wag Tg(KRT5-SOS1)892A6Wag/0 involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL	decreased tumor growth/size	J:175064
	increased skin papilloma incidence	J:175064
	increased skin tumor incidence	J:175064
Egfr^wa2/Egfr⁺ Fos^tm6.1Wag/Fos^tm6.1Wag Tg(KRT5-SOS1)892A6Wag/0 involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL	increased skin papilloma incidence	J:175064
	increased tumor growth/size	J:175064
Fos^tm1.1Fawa/Fos^tm1.1Fawa involves: 129 * 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:101977
Fos^tm1Wag/Fos^tm1Wag Trp53^tm1Tyj/Trp53⁺ involves: 129S2/SvPas * C57BL/6	increased rhabdomyosarcoma incidence	J:89283
Fos^tm1Wag/Fos^tm1Wag Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S2/SvPas * C57BL/6	increased rhabdomyosarcoma incidence	J:89283
	osteopetrosis	J:89283
Fos^tm1Wag/Fos^{tm2(Fosl1)Wag} involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal bone marrow cavity morphology	J:65766
	absent teeth	J:65766
	decreased body size	J:65766
	decreased osteoclast cell number	J:65766
	failure of tooth eruption	J:65766
	increased retina apoptosis	J:65766
	osteopetrosis	J:65766
Fos^{tm2(Fosl1)Wag}/Fos^{tm2(Fosl1)Wag} involves: 129P2/OlaHsd * C57BL/6	abnormal spatial learning	J:94200
	normal behavior/neurological phenotype	J:94200
	normal growth/size/body region phenotype	J:65766
	increased retina apoptosis	J:65766
	normal nervous system phenotype	J:94200
	normal skeleton phenotype	J:65766

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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