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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		G6pc1
glucose-6-phosphatase catalytic subunit 1
MGI:95607
47 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
G6pc1em1Jyc/G6pc1em1Jyc
involves: 129S4/SvJae * C57BL/6 		abnormal homeostasis J:320697
abnormal liver sinusoid morphology J:320697
abnormal renal glomerulus morphology J:320697
abnormal renal tubule epithelium morphology J:320697
decreased body size J:320697
enlarged kidney J:320697
enlarged liver J:320697
hepatic steatosis J:320697
normal homeostasis/metabolism phenotype J:320697
hypoglycemia J:320697
increased blood uric acid level J:320697
increased circulating cholesterol level J:320697
increased circulating triglyceride level J:320697
increased liver glycogen level J:320697
increased liver triglyceride level J:320697
normal renal/urinary system phenotype J:320697
slow postnatal weight gain J:320697
G6pc1tm1.1Ics/G6pc1tm1.1Ics
Albtm1(cre/ERT2)Mtz/Alb+
involves: 129S2/SvPas * C57BL/6J 		abnormal blood homeostasis J:195257
abnormal hepatocyte morphology J:195257
enlarged liver J:195257
hepatic steatosis J:195257
normal homeostasis/metabolism phenotype J:195257
increased blood uric acid level J:195257
increased circulating cholesterol level J:195257
increased circulating triglyceride level J:195257
increased liver adenoma incidence J:195257
increased liver glycogen level J:195257
increased liver triglyceride level J:195257
increased liver weight J:195257
pale liver J:195257
G6pc1tm1.1Ics/G6pc1tm1.1Ics
Tg(Kap-cre/ERT2)64.9Ics/0
involves: 129S2/SvPas * FVB/N 		abnormal kidney cortex morphology J:238264
abnormal kidney morphology J:238264
abnormal podocyte morphology J:238264
abnormal renal tubule morphology J:238264
abnormal urine homeostasis J:238264
decreased urine pH J:238264
enlarged kidney J:238264
increased blood uric acid level J:238264
increased kidney glycogen level J:238264
increased kidney weight J:238264
increased urine magnesium level J:238264
increased urine microalbumin level J:238264
increased urine phosphate level J:238264
increased urine uric acid level J:238264
G6pc1tm1Jyc/G6pc1tm1Jyc
involves: 129S4/SvJae 		abnormal cartilage development J:33212
abnormal glucose homeostasis J:33212
abnormal joint morphology J:33212
abnormal lipid homeostasis J:33212
abnormal long bone epiphyseal plate morphology J:33212
abnormal renal tubule epithelium morphology J:33212
decreased circulating glucose level J:33212
dilated renal tubule J:33212
enlarged kidney J:33212
enlarged liver J:33212
hepatic necrosis J:33212
hepatic steatosis J:33212
increased blood uric acid level J:33212
increased circulating cholesterol level J:33212
increased circulating triglyceride level J:33212
increased kidney glycogen level J:33212
increased liver glycogen level J:33212
postnatal growth retardation J:33212
premature death J:33212
renal glomerulus atrophy J:33212
renal tubule atrophy J:33212
seizures J:33212
G6pc1tm2.2Jyc/G6pc1tm2.2Jyc
involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6J * FVB/N 		abnormal blood homeostasis J:155990
hypoglycemia J:155990
increased blood uric acid level J:155990
increased circulating cholesterol level J:155990
increased circulating triglyceride level J:155990
increased kidney glycogen level J:155990
increased kidney weight J:155990
increased liver glycogen level J:155990
increased liver weight J:155990
postnatal growth retardation J:155990
seizures J:155990
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory