Gad1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gad1
glutamate decarboxylase 1
MGI:95632

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gad1^{tm1(Gria2)Mony}/Gad1^{tm1(Gria2)Mony} involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal brain wave pattern	J:134013
	abnormal excitatory postsynaptic potential	J:134013
Gad1^tm1.1Tama/Gad1⁺ Pcnt^m239Asp/Pcnt^m239Asp involves: C57BL/6 * C57BL/6J * CBA * FVB/N	abnormal neuronal migration	J:158418
	abnormal neuronal precursor proliferation	J:158418
	decreased brain size	J:158418
	embryonic growth retardation	J:158418
	increased apoptosis	J:158418
	perinatal lethality	J:158418
	preaxial polydactyly	J:158418
	small olfactory bulb	J:158418
	thin cerebral cortex	J:158418
Gad1^tm1.1Tama/Gad1⁺ Pkd2l1^tm1.1Yuni/Pkd2l1^tm1.1Yuni involves: 129S/SvEv * C57BL/6 * CBA	abnormal gustatory system physiology	J:172581
	abnormal nerve fiber response	J:172581
Gad1^tm1Oba/Gad1⁺ Gad2^tm1Oba/Gad2^tm1Oba involves: C57BL/6 * CBA	lethality throughout fetal growth and development, incomplete penetrance	J:102619
	premature death	J:102619
Gad1^tm1Oba/Gad1^tm1Oba Gad2^tm1Oba/Gad2^tm1Oba involves: C57BL/6 * CBA	cleft palate	J:102619
	decreased gamma-aminobutyric acid level	J:102619
	neonatal lethality, complete penetrance	J:102619
	normal nervous system phenotype	J:102619
Gad1^tm1Tama/Gad1^tm1Tama Gad2^tm1Oba/Gad2^tm1Oba involves: C57BL/6 * CBA	abnormal nerve fiber response	J:122055
	abnormal nervous system electrophysiology	J:122055
	cleft palate	J:122055
	omphalocele	J:122055
	primary atelectasis	J:122055
	respiratory failure	J:122055
Gad1^tm1Tama/? Lhx6^tm2Vpa/Lhx6^tm2Vpa involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA	abnormal neuronal migration	J:119476
	lethality throughout fetal growth and development, incomplete penetrance	J:119476

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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