Gad2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gad2
glutamic acid decarboxylase 2
MGI:95634

27 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gad2^{tm1(cre/ERT2)Zjh}/Gad2⁺ involves: 129S4/SvJae * C57BL/6 * SJL	no abnormal phenotype detected	J:151755
Gad2^tm1.1Ksvo/Gad2^tm1.1Ksvo involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:101977
Gad2^{tm1b(EUCOMM)Wtsi}/Gad2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Gad2^{tm1b(EUCOMM)Wtsi}/Ieg	abnormal behavior	J:211773
	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	decreased prepulse inhibition	J:211773
	decreased respiratory quotient	J:211773
	impaired glucose tolerance	J:211773
	increased anxiety-related response	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating chloride level	J:211773
	increased circulating sodium level	J:211773
	increased fasting circulating glucose level	J:211773
	increased thigmotaxis	J:211773
	increased vertical activity	J:211773
Gad2^tm1Bae/Gad2^tm1Bae involves: 129X1/SvJ	normal nervous system phenotype	J:126581
Gad2^tm1Bae/Gad2^tm1Bae involves: 129X1/SvJ * C57BL/6	normal homeostasis/metabolism phenotype	J:44638
	premature death	J:44638
	normal reproductive system phenotype	J:44638
	seizures	J:44638
Gad2^tm1Bae/Gad2^tm1Bae involves: 129X1/SvJ * NOD	decreased gamma-aminobutyric acid level	J:44638
	premature death	J:44638
	normal reproductive system phenotype	J:44638
	seizures	J:44638
Gad2^tm1Miya/Gad2^tm1Miya NOD.129P2-Gad2^tm1Miya	decreased body weight	J:88785
	increased circulating glucose level	J:88785
	pancreas inflammation	J:88785
	premature death	J:88785
	seizures	J:88785
Gad2^tm1Oba/Gad2⁺ involves: C57BL/6 * CBA	decreased aggression towards male mice	J:62320
	decreased gamma-aminobutyric acid level	J:62320
	increased anxiety-related response	J:62320
	seizures	J:37576
Gad2^tm1Oba/Gad2^tm1Oba involves: C57BL/6 * CBA	decreased aggression towards male mice	J:62320
	decreased gamma-aminobutyric acid level	J:62320
	increased anxiety-related response	J:62320
	increased coping response	J:62320
	myoclonus	J:62320
	normal nervous system phenotype	J:62320
	premature death	J:62320
	seizures	J:37576, J:62320
	tonic-clonic seizures	J:62320
Gad2^tm2(cre)Zjh/Gad2^tm2(cre)Zjh involves: 129S4/SvJae * C57BL/6 * SJL	no abnormal phenotype detected	J:151755

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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