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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gad2
glutamic acid decarboxylase 2
MGI:95634
20 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gabrdtm1.1Jmag/Gabrd+
Gad2tm2(cre)Zjh/Gad2+
involves: 129S4/SvJae * C57BL/6 * SJL 		abnormal CNS synaptic transmission J:203336
abnormal GABAergic neuron physiology J:203336
abnormal inhibitory postsynaptic currents J:203336
decreased susceptibility to pharmacologically induced seizures J:203336
impaired ability to fire action potentials J:203336
increased excitatory postsynaptic current amplitude J:203336
Gad1tm1Oba/Gad1+
Gad2tm1Oba/Gad2tm1Oba
involves: C57BL/6 * CBA 		lethality throughout fetal growth and development, incomplete penetrance J:102619
premature death J:102619
Gad1tm1Oba/Gad1tm1Oba
Gad2tm1Oba/Gad2tm1Oba
involves: C57BL/6 * CBA 		cleft palate J:102619
decreased gamma-aminobutyric acid level J:102619
neonatal lethality, complete penetrance J:102619
normal nervous system phenotype J:102619
Gad1tm1Tama/Gad1tm1Tama
Gad2tm1Oba/Gad2tm1Oba
involves: C57BL/6 * CBA 		abnormal nerve fiber response J:122055
abnormal nervous system electrophysiology J:122055
cleft palate J:122055
omphalocele J:122055
primary atelectasis J:122055
respiratory failure J:122055
Gad2tm2(cre)Zjh/?
Rai1tm2.1Luo/Rai1tm2.1Luo
either: (involves: 129S1/Sv * 129S4/SvJae * C57BL/6) or (involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6) 		abnormal associative learning J:237687
impaired contextual conditioning behavior J:237687
impaired cued conditioning behavior J:237687
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory