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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gapdh
glyceraldehyde-3-phosphate dehydrogenase
MGI:95640
19 phenotypes from 10 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gapdhem1(IMPC)Mbp/Gapdh+
C57BL/6N-Gapdhem1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal retina morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
embryonic growth retardation J:211773
Gapdhem1(IMPC)Mbp/Gapdhem1(IMPC)Mbp
C57BL/6N-Gapdhem1(IMPC)Mbp/MbpMmucd 		embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Gapdhm1Neu/Gapdh+
C3.Cg-Gapdhm1Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
Gapdhm1Neu/Gapdh+
involves: 101/El * C3H/El 		abnormal enzyme/coenzyme activity J:15477
Gapdhm1Neu/Gapdhm1Neu
C3.Cg-Gapdhm1Neu 		embryonic lethality between implantation and somite formation, incomplete penetrance J:126359
Gapdhm1Neu/Gapdhm1Neu
involves: 101/El * C3H/El 		preweaning lethality, complete penetrance J:11216, J:15477
Gapdhm2Neu/Gapdh+
C3.Cg-Gapdhm2Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
Gapdhm2Neu/Gapdh+
involves: 101/El * C3H/El 		abnormal enzyme/coenzyme activity J:15476
Gapdhm2Neu/Gapdhm2Neu
C3.Cg-Gapdhm2Neu 		embryonic lethality between implantation and somite formation, incomplete penetrance J:126359
Gapdhm2Neu/Gapdhm2Neu
involves: 101/El * C3H/El 		preweaning lethality, complete penetrance J:11216, J:15476
Gapdhm3Neu/Gapdh+
C3.Cg-Gapdhm3Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
Gapdhm3Neu/Gapdh+
involves: 101/El * C3H/El 		abnormal enzyme/coenzyme activity J:15477
Gapdhm3Neu/Gapdhm3Neu
C3.Cg-Gapdhm3Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
decreased survivor rate J:126359
preweaning lethality, complete penetrance J:126359
Gapdhm3Neu/Gapdhm3Neu
involves: 101/El * C3H/El 		abnormal enzyme/coenzyme activity J:15477
preweaning lethality, complete penetrance J:11216, J:15477
Gapdhm4Neu/Gapdh+
C3.Cg-Gapdhm4Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
preweaning lethality, incomplete penetrance J:126359
Gapdhm4Neu/Gapdh+
involves: 101/El * C3H/El 		abnormal enzyme/coenzyme activity J:15476
Gapdhm4Neu/Gapdhm4Neu
C3.Cg-Gapdhm4Neu 		embryonic lethality between implantation and somite formation, incomplete penetrance J:126359
Gapdhm4Neu/Gapdhm4Neu
involves: 101/El * C3H/El 		preweaning lethality, complete penetrance J:11216, J:15476
GapdhM5Neu/Gapdh+
C3.Cg-GapdhM5Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
GapdhM5Neu/GapdhM5Neu
C3.Cg-GapdhM5Neu 		preweaning lethality, complete penetrance J:126359
GapdhM6Neu/Gapdh+
C3.Cg-GapdhM6Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
preweaning lethality, incomplete penetrance J:126359
GapdhM6Neu/GapdhM6Neu
C3.Cg-GapdhM6Neu 		abnormal hematocrit J:126359
normal cardiovascular system phenotype J:126359
decreased hemoglobin content J:126359
normal growth/size/body region phenotype J:126359
normal hematopoietic system phenotype J:126359
normal liver/biliary system phenotype J:126359
preweaning lethality, complete penetrance J:126359
normal renal/urinary system phenotype J:126359
GapdhM7Neu/Gapdh+
C3.Cg-GapdhM7Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
GapdhM7Neu/GapdhM7Neu
C3.Cg-GapdhM7Neu 		preweaning lethality, complete penetrance J:126359
GapdhM8Neu/Gapdh+
C3.Cg-GapdhM8Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
GapdhM8Neu/GapdhM8Neu
C3.Cg-GapdhM8Neu 		preweaning lethality, complete penetrance J:126359
GapdhM9Neu/Gapdh+
C3.Cg-GapdhM9Neu 		decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity J:126359
GapdhM9Neu/GapdhM9Neu
C3.Cg-GapdhM9Neu 		preweaning lethality, complete penetrance J:126359
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/29/2024
MGI 6.24 		The Jackson Laboratory