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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gata1
GATA binding protein 1
MGI:95661
87 phenotypes from 19 alleles in 21 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gata1Plt13/Y
BALB/c-Gata1Plt13 		anemia J:113720
decreased embryo size J:113720
embryo tissue necrosis J:113720
embryonic lethality during organogenesis, incomplete penetrance J:113720
lethality throughout fetal growth and development, complete penetrance J:113720
small liver J:113720
Gata1Plt13/Gata1+
BALB/c-Gata1Plt13 		abnormal megakaryocyte morphology J:113720
abnormal megakaryocyte progenitor cell morphology J:113720
abnormal myelopoiesis J:113720
abnormal thrombopoiesis J:113720
enlarged spleen J:113720
extramedullary hematopoiesis J:113720
increased megakaryocyte cell number J:113720
increased spleen weight J:113720
polyploidy J:113720
thrombocytopenia J:113720
Gata1tm1.1Yen/Gata1tm1.1Yen
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N 		abnormal erythropoiesis J:200716
decreased erythroid progenitor cell number J:200716
normal hematopoietic system phenotype J:200716
Gata1tm1Mym/Gata1+
involves: 129P2/OlaHsd 		abnormal erythropoiesis J:88685
abnormal megakaryocyte morphology J:88685
abnormal proerythroblast morphology J:88685
anemia J:88685
decreased hematocrit J:88685
decreased spleen red pulp amount J:88685
decreased spleen white pulp amount J:88685
decreased survivor rate J:88685
enlarged spleen J:88685
extramedullary hematopoiesis J:88685
pale spleen J:88685
premature death J:88685
thrombocytopenia J:88685
Gata1tm1Mym/Y
involves: 129P2/OlaHsd 		abnormal iron level J:58508
Gata1tm1Mym/Y
involves: 129P2/OlaHsd * BALB/c 		abnormal embryonic erythropoiesis J:40321
absent vitelline blood vessels J:40321
anemia J:40321
decreased embryo size J:40321
decreased erythroid progenitor cell number J:40321
embryonic lethality during organogenesis, complete penetrance J:40321
pale liver J:40321
pale yolk sac J:40321
Gata1tm1Mym/Gata1+
involves: 129P2/OlaHsd * BALB/c 		abnormal erythropoiesis J:40321
anemia J:40321
Gata1tm1Mym/Gata1tm1Mym
Tg(Gata1)#Mym/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J 		normal hematopoietic system phenotype J:158252
Gata1tm1Mym/Y
Tg(Gata1)#Mym/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J 		normal hematopoietic system phenotype J:158252
Gata1tm1Mym/Y
Tg(Gata1*V205G)1Mym/0
involves: C57BL/6 * DBA/2 		abnormal bone marrow cell morphology/development J:89054
abnormal erythrocyte morphology J:89054
abnormal megakaryocyte differentiation J:89054
abnormal megakaryocyte morphology J:89054
abnormal mononuclear cell morphology J:89054
abnormal platelet morphology J:89054
abnormal stress erythropoiesis J:89054
abnormal thrombopoiesis J:89054
anisocytosis J:89054
decreased fetal size J:89054
increased megakaryocyte cell number J:89054
pallor J:89054
thrombocytopenia J:89054
Gata1tm1Phi/Y
involves: 129P2/OlaHsd * C57BL/6 * FVB 		no abnormal phenotype detected J:85598
Gata1tm1Phi/Gata1+
Tg(HBB-cre)1Phi/0
involves: FVB 		abnormal erythropoiesis J:98277
anemia J:98277
Gata1tm1Phi/Gata1+
Tg(HBB-cre)1Phi/0
Tg(HBB-Gata1)G4Phi/0
involves: FVB 		abnormal erythropoiesis J:98277
anemia J:98277
lethality throughout fetal growth and development, complete penetrance J:98277
Gata1tm1Phi/Gata1+
Tg(HBB-Gata1)G4Phi/0
involves: FVB 		abnormal erythropoiesis J:98277
Gata1tm1Phi/Gata1tm1Phi
involves: 129P2/OlaHsd * C57BL/6 * FVB 		no abnormal phenotype detected J:85598
Gata1tm1Phi/Y
Tg(Dhh-cre)1Mejr/0
involves: 129P2/OlaHsd * C57BL/6 * FVB 		no abnormal phenotype detected J:85598
Gata1tm1Sho/Gata1+
involves: 129S4/SvJae * C57BL/6 		anemia J:36249
decreased eosinophil cell number J:88711
Gata1tm1Sho/Y
involves: 129S4/SvJae * C57BL/6 		abnormal erythropoiesis J:36249
anemia J:36249
embryonic lethality during organogenesis, complete penetrance J:36249
Gata1tm1Sho/Gata1tm1Sho
Tg(Gata1)#Mym/0
involves: 129S4/SvJae * C57BL/6 * DBA/2J 		normal hematopoietic system phenotype J:158252
Gata1tm1Sho/Y
Tg(Gata1)#Mym/0
involves: 129S4/SvJae * C57BL/6 * DBA/2J 		normal hematopoietic system phenotype J:158252
Gata1tm2.1Sho/Y
involves: 129S4/SvJae * C57BL/6 		abnormal megakaryocyte differentiation J:41605
abnormal megakaryocyte morphology J:41605
abnormal megakaryocyte progenitor cell morphology J:41605
normal hematopoietic system phenotype J:41605
increased mean platelet volume J:41605
increased megakaryocyte cell number J:41605
thrombocytopenia J:41605
Gata1tm2.1Sho/Gata1+
involves: 129S4/SvJae * C57BL/6 		abnormal megakaryocyte differentiation J:41605
abnormal megakaryocyte progenitor cell morphology J:41605
increased megakaryocyte cell number J:41605
Gata1tm2.1Sho/Gata1tm2.1Sho
involves: 129/Sv * 129S4/SvJae 		abnormal hematopoietic system physiology J:106670
Gata1tm2.1Yen/Gata1tm2.1Yen
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N 		normal hematopoietic system phenotype J:200716
Gata1tm2Sho/Y
involves: 129S4/SvJae * C57BL/6 		abnormal megakaryocyte differentiation J:41605
abnormal megakaryocyte morphology J:41605
abnormal megakaryocyte progenitor cell morphology J:41605
anemia J:41605
decreased survivor rate J:41605
increased mean platelet volume J:41605
increased megakaryocyte cell number J:41605
thrombocytopenia J:41605
Gata1tm2Sho/Gata1+
involves: 129S4/SvJae * C57BL/6 		abnormal megakaryocyte differentiation J:41605
abnormal megakaryocyte progenitor cell morphology J:41605
increased megakaryocyte cell number J:41605
Gata1tm2Sho/Y
involves: 129S4/SvJae * C57BL/6 * CD-1 		abnormal bone marrow morphology J:78348, J:78540
abnormal common myeloid progenitor cell morphology J:78348, J:78540
abnormal definitive hematopoiesis J:78348
abnormal erythroid progenitor cell morphology J:78348, J:78540
abnormal hematocrit J:78540
abnormal liver morphology J:78348
abnormal megakaryocyte progenitor cell morphology J:78348
abnormal physiological response to xenobiotic J:78540
abnormal platelet shape J:78348, J:78540
abnormal spleen morphology J:78348
abnormal spleen red pulp morphology J:78540
anemia J:78348
decreased bone marrow cell number J:78348, J:78540
decreased erythrocyte cell number J:78348
decreased erythroid progenitor cell number J:78540
decreased hematocrit J:78348
decreased lymphocyte cell number J:78348
enlarged spleen J:78348, J:78540
extramedullary hematopoiesis J:78540
increased bone ossification J:78348
increased bone trabecula number J:78348
increased erythroid progenitor cell number J:78348, J:78540
increased neutrophil cell number J:78348
increased number of Howell-Jolly bodies J:78348
increased splenocyte number J:78540
myelofibrosis J:78348
poikilocytosis J:78348
polychromatophilia J:78348
postnatal lethality, incomplete penetrance J:78348
premature death J:78348
prenatal lethality, incomplete penetrance J:78348
thrombocytopenia J:78348, J:78540
Gata1tm2Sho/Gata1tm2Sho
involves: 129S4/SvJae 		increased bone ossification J:111270
increased compact bone volume J:111270
increased osteoblast cell number J:111270
increased osteoclast cell number J:111270
increased trabecular bone volume J:111270
Gata1tm2Sho/Gata1tm2Sho
involves: 129S4/SvJae * C57BL/6 * CD-1 		abnormal bone marrow morphology J:78348, J:78540
abnormal common myeloid progenitor cell morphology J:78348, J:78540
abnormal definitive hematopoiesis J:78348
abnormal erythroid progenitor cell morphology J:78348, J:78540
abnormal hematocrit J:78540
abnormal liver morphology J:78348
abnormal megakaryocyte progenitor cell morphology J:78348
abnormal physiological response to xenobiotic J:78540
abnormal platelet shape J:78348, J:78540
abnormal spleen morphology J:78348
abnormal spleen red pulp morphology J:78540
anemia J:78348
decreased bone marrow cell number J:78348, J:78540
decreased erythrocyte cell number J:78348
decreased erythroid progenitor cell number J:78540
decreased hematocrit J:78348
decreased lymphocyte cell number J:78348
enlarged spleen J:78348, J:78540
extramedullary hematopoiesis J:78540
increased bone ossification J:78348
increased bone trabecula number J:78348
increased erythroid progenitor cell number J:78348, J:78540
increased neutrophil cell number J:78348
increased number of Howell-Jolly bodies J:78348
increased splenocyte number J:78540
myelofibrosis J:78348
poikilocytosis J:78348
polychromatophilia J:78348
postnatal lethality, incomplete penetrance J:78348
premature death J:78348
prenatal lethality, incomplete penetrance J:78348
thrombocytopenia J:78348, J:78540
Gata1tm4Sho/Y
involves: 129S6/SvEvTac * C57BL/6 		abnormal erythropoiesis J:77724
abnormal megakaryocyte differentiation J:77724
abnormal megakaryocyte progenitor cell morphology J:77724
anemia J:77724
embryonic lethality during organogenesis, incomplete penetrance J:77724
neonatal lethality, complete penetrance J:77724
Gata1tm5(GATA3)Sho/Y
involves: 129S4/SvJae * C57BL/6 		abnormal erythropoiesis J:47295
anemia J:47295
decreased embryo size J:47295
embryonic lethality during organogenesis, complete penetrance J:47295
enlarged pericardium J:47295
pale yolk sac J:47295
pallor J:47295
Gata1tm5(GATA3)Sho/Gata1+
involves: 129S4/SvJae * C57BL/6 		abnormal definitive hematopoiesis J:47295
anemia J:47295
decreased erythrocyte cell number J:47295
decreased survivor rate J:47295
embryonic lethality during organogenesis, incomplete penetrance J:47295
lethality throughout fetal growth and development, incomplete penetrance J:47295
pale yolk sac J:47295
pallor J:47295
Gata1tm6Sho/Y
involves: 129S1/Sv 		decreased eosinophil cell number J:88711
decreased erythrocyte cell number J:88711
decreased hematocrit J:88711
enlarged spleen J:88711
normal hematopoietic system phenotype J:88711
Gata1tm6Sho/Gata1tm6Sho
C.129S1-Gata1tm6Sho 		abnormal skin physiology J:182213
autoimmune response J:182213
Gata1tm6Sho/Gata1tm6Sho
involves: 129S1/Sv 		decreased eosinophil cell number J:88711
normal hematopoietic system phenotype J:88711
Gata1tm6Sho/Gata1tm6Sho
involves: 129S1/Sv * BALB/c 		abnormal bronchiole morphology J:92849
abnormal hemostasis J:115273
abnormal leukocyte cell number J:115273
abnormal respiratory system physiology J:92849
decreased circulating interleukin-4 level J:115273
decreased circulating interleukin-13 level J:115273
decreased eosinophil cell number J:115273
decreased lymphocyte cell number J:115273
increased neutrophil cell number J:115273
normal respiratory system phenotype J:92849
Gata1tm7Sho/Y
involves: 129S1/Sv * C57BL/6 		abnormal erythropoiesis J:99310
abnormal megakaryocyte progenitor cell morphology J:99310
liver hypoplasia J:99310
pale liver J:99310
Gata1tm7Sho/Gata1tm7Sho
involves: 129S1/Sv * C57BL/6 		abnormal erythropoiesis J:99310
abnormal megakaryocyte progenitor cell morphology J:99310
liver hypoplasia J:99310
pale liver J:99310
Gata1tm8.1Sho/Y
involves: 129S1/Sv * C57BL/6 		abnormal megakaryocyte morphology J:99310
Gata1tm8.1Sho/Gata1tm8.1Sho
involves: 129S1/Sv * C57BL/6 		abnormal megakaryocyte morphology J:99310
Gata1tm8.2Sho/Y
involves: 129S1/Sv 		abnormal erythropoiesis J:99310
abnormal megakaryocyte morphology J:99310
liver hypoplasia J:99310
pale liver J:99310
Gata1tm8.2Sho/Gata1tm8.2Sho
involves: 129S1/Sv 		abnormal erythropoiesis J:99310
abnormal megakaryocyte morphology J:99310
liver hypoplasia J:99310
pale liver J:99310
Gata1tm9Sho/Y
involves: C57BL/6 		normal hematopoietic system phenotype J:132560
Gata1tm9Sho/Y
Not Specified 		impaired hematopoiesis J:100411
Gata1tm10Sho/Y
involves: C57BL/6 		decreased erythroid progenitor cell number J:132560
normal hematopoietic system phenotype J:132560
Tg(HBB-Gata1)G4Phi/Y
involves: 129P2/OlaHsd * FVB 		abnormal erythropoiesis J:63773
anemia J:63773
lethality throughout fetal growth and development, incomplete penetrance J:63773
Tg(HBB-Gata1)G4Phi/0
involves: 129P2/OlaHsd * FVB 		no abnormal phenotype detected J:63773
Tg(HBB-Gata1)G4Phi/Y
involves: FVB 		abnormal erythropoiesis J:98277
anemia J:98277
lethality throughout fetal growth and development, incomplete penetrance J:98277
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11/12/2024
MGI 6.24 		The Jackson Laboratory