Gbx2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gbx2
gastrulation brain homeobox 2
MGI:95668

28 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gbx2^{tm1.1(cre/ERT2)Jyhl}/Gbx2^tm1.1Mrt Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	abnormal telencephalon development	J:147282
	abnormal thalamus morphology	J:147282
Gbx2^{tm1.1(cre/ERT2)Jyhl}/Gbx2^tm1Mrt Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	abnormal thalamus morphology	J:147282
Gbx2^tm1.1Mrt/Gbx2⁺ Fgf8^tm1.4Mrt/Fgf8⁺ B6.129-Gbx2^tm1.1Mrt Fgf8^tm1.4Mrt	abnormal pharyngeal arch artery morphology	J:100584
	retroesophageal right subclavian artery	J:100584
	right aortic arch	J:100584
Gbx2^tm1.1Mrt/Gbx2^tm1.1Mrt Fgf8^tm1.4Mrt/Fgf8⁺ B6.129-Gbx2^tm1.1Mrt Fgf8^tm1.4Mrt	abnormal neural crest cell migration	J:100584
	abnormal pharyngeal arch artery morphology	J:100584
	abnormal thymus development	J:100584
	interrupted aortic arch, type b	J:100584
	retroesophageal right subclavian artery	J:100584
	right aortic arch	J:100584
	small ears	J:100584
	small mandible	J:100584
Gbx2^tm1.1Mrt/Gbx2^tm1.1Mrt Otx2^{tm1(OTX1)Asim}/Otx2^{tm1(OTX1)Asim} involves: 129 * C57BL/6 * DBA/2	abnormal embryonic neuroepithelium morphology	J:72725
	abnormal heart morphology	J:72725
	abnormal neural plate morphology	J:72725
	abnormal neural tube morphology	J:72725
	absent embryonic telencephalon	J:72725
	absent midbrain-hindbrain boundary	J:72725
	absent nasal placodes	J:72725
	absent optic placodes	J:72725
	absent optic vesicle	J:72725
	absent pharyngeal arches	J:72725
	decreased embryo size	J:72725
	dilated heart	J:72725
	embryonic lethality during organogenesis, complete penetrance	J:72725
	exencephaly	J:72725
Gbx2^tm1.1Mrt/Gbx2^tm1.1Mrt Otx2^tm1Pas/Otx2^tm2Asim involves: 129 * C57BL/6 * DBA/2	abnormal brain development	J:72725
	abnormal head development	J:72725
	normal cardiovascular system phenotype	J:72725
	normal mortality/aging	J:72725

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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