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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gdf1
growth differentiation factor 1
MGI:95683
28 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Acvr1btm1Enl/Acvr1b+
Gdf1tm1Sjl/Gdf1+
Nodaltm1Rob/Nodal+
involves: 129/Sv * C57BL/6 		abnormal forebrain morphology J:108723
abnormal nasal septum morphology J:108723
Acvr1btm1Enl/Acvr1b+
Gdf1tm1Sjl/Gdf1tm1Sjl
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		abnormal primitive streak formation J:108723
holoprosencephaly J:108723
rostral body truncation J:108723
Acvr1ctm1Cfi/Acvr1c+
Gdf1tm1Sjl/Gdf1+
Nodaltm1Rob/Nodal+
involves: 129 * C57BL/6 		no abnormal phenotype detected J:108723
Gdf1tm1Sjl/Gdf1+
Gdf3Gt(AD0857)Wtsi/Gdf3+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:127541
Gdf1tm1Sjl/Gdf1+
Gdf3Gt(AD0857)Wtsi/Gdf3Gt(AD0857)Wtsi
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal anterior visceral endoderm cell migration J:127541
abnormal primitive streak elongation J:127541
abnormal primitive streak formation J:127541
absent anterior visceral endoderm J:127541
absent mesoderm J:127541
decreased survivor rate J:127541
embryonic lethality between implantation and somite formation, incomplete penetrance J:127541
Gdf1tm1Sjl/Gdf1tm1Sjl
Gdf3Gt(AD0857)Wtsi/Gdf3+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:127541
Gdf1tm1Sjl/Gdf1tm1Sjl
Gdf3Gt(AD0857)Wtsi/Gdf3Gt(AD0857)Wtsi
involves: 129P2/OlaHsd * C57BL/6 		abnormal primitive streak elongation J:127541
abnormal primitive streak formation J:127541
absent anterior visceral endoderm J:127541
absent mesoderm J:127541
decreased survivor rate J:127541
embryonic lethality between implantation and somite formation, incomplete penetrance J:127541
Gdf1tm1Sjl/Gdf1tm1Sjl
Nodaltm1Rob/Nodal+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal diencephalon morphology J:108723
abnormal first pharyngeal arch morphology J:108723
abnormal foregut morphology J:108723
abnormal mesendoderm development J:108723
abnormal neural fold formation J:108723
abnormal neural plate morphology J:108723
abnormal third ventricle morphology J:108723
absent mandible J:108723
absent notochord J:108723
absent prechordal plate J:108723
absent tongue J:108723
cleft upper lip J:108723
embryonic lethality during organogenesis, incomplete penetrance J:108723
fused first pharyngeal arch J:108723
holoprosencephaly J:108723
nasal septum hypoplasia J:108723
truncated notochord J:108723
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory