About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gdf1
growth differentiation factor 1
MGI:95683
28 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Acvr1btm1Enl/Acvr1b+
Gdf1tm1Sjl/Gdf1+
Nodaltm1Rob/Nodal+
involves: 129/Sv * C57BL/6 		abnormal forebrain morphology J:108723
abnormal nasal septum morphology J:108723
Acvr1btm1Enl/Acvr1b+
Gdf1tm1Sjl/Gdf1tm1Sjl
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		abnormal primitive streak formation J:108723
holoprosencephaly J:108723
rostral body truncation J:108723
Acvr1ctm1Cfi/Acvr1c+
Gdf1tm1Sjl/Gdf1+
Nodaltm1Rob/Nodal+
involves: 129 * C57BL/6 		no abnormal phenotype detected J:108723
Gdf1tm1Sjl/Gdf1+
Gdf3Gt(AD0857)Wtsi/Gdf3+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:127541
Gdf1tm1Sjl/Gdf1+
Gdf3Gt(AD0857)Wtsi/Gdf3Gt(AD0857)Wtsi
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal anterior visceral endoderm cell migration J:127541
abnormal primitive streak elongation J:127541
abnormal primitive streak formation J:127541
absent anterior visceral endoderm J:127541
absent mesoderm J:127541
decreased survivor rate J:127541
embryonic lethality between implantation and somite formation, incomplete penetrance J:127541
Gdf1tm1Sjl/Gdf1tm1Sjl
Gdf3Gt(AD0857)Wtsi/Gdf3+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:127541
Gdf1tm1Sjl/Gdf1tm1Sjl
Gdf3Gt(AD0857)Wtsi/Gdf3Gt(AD0857)Wtsi
involves: 129P2/OlaHsd * C57BL/6 		abnormal primitive streak elongation J:127541
abnormal primitive streak formation J:127541
absent anterior visceral endoderm J:127541
absent mesoderm J:127541
decreased survivor rate J:127541
embryonic lethality between implantation and somite formation, incomplete penetrance J:127541
Gdf1tm1Sjl/Gdf1tm1Sjl
Nodaltm1Rob/Nodal+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal diencephalon morphology J:108723
abnormal first pharyngeal arch morphology J:108723
abnormal foregut morphology J:108723
abnormal mesendoderm development J:108723
abnormal neural fold formation J:108723
abnormal neural plate morphology J:108723
abnormal third ventricle morphology J:108723
absent mandible J:108723
absent notochord J:108723
absent prechordal plate J:108723
absent tongue J:108723
cleft upper lip J:108723
embryonic lethality during organogenesis, incomplete penetrance J:108723
fused first pharyngeal arch J:108723
holoprosencephaly J:108723
nasal septum hypoplasia J:108723
truncated notochord J:108723
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory