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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gdf3
growth differentiation factor 3
MGI:95686
26 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gdf3Gt(AD0857)Wtsi/Gdf3Gt(AD0857)Wtsi
involves: 129P2/OlaHsd * C57BL/6 		abnormal anterior visceral endoderm cell migration J:127541
abnormal primitive streak elongation J:127541
abnormal primitive streak formation J:127541
absent anterior visceral endoderm J:127541
absent mesoderm J:127541
decreased survivor rate J:127541
embryonic lethality between implantation and somite formation, incomplete penetrance J:127541
rostral body truncation J:127541
Gdf3tm1Mms/Gdf3tm1Mms
either: B6.129-Gdf3tm1Mms or (involves: 129S7/SvEvBrd * C57BL/6J) 		abnormal anterior visceral endoderm cell migration J:104371
abnormal anterior visceral endoderm morphology J:104371
abnormal developmental patterning J:104371
abnormal endoderm development J:104371
abnormal mesoderm development J:104371
abnormal primitive streak formation J:104371
abnormal rostral-caudal axis patterning J:104371
absent endoderm J:104371
embryonic lethality, complete penetrance J:104371
embryonic-extraembryonic boundary constriction J:104371
rostral-caudal axis duplication J:104371
split notochord J:104371
thin endoderm J:104371
Gdf3tm1Zuk/Gdf3tm1Zuk
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal fat cell morphology J:143083
decreased survivor rate J:143083
decreased susceptibility to diet-induced obesity J:143083
decreased white adipose tissue amount J:143083
normal growth/size/body region phenotype J:143083
improved glucose tolerance J:143083
increased basal metabolism J:143083
prenatal lethality, incomplete penetrance J:143083
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory