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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gdf5
growth differentiation factor 5
MGI:95688
61 phenotypes from 12 alleles in 13 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gdf5bp-3J/Gdf5bp-3J
involves: BALB/cJ 		abnormal carpal bone morphology J:17582, J:38423
abnormal digit development J:17582
abnormal digit morphology J:17582, J:38423
abnormal limb mesenchyme morphology J:17582
abnormal metacarpal bone morphology J:38423
abnormal metatarsal bone morphology J:38423
abnormal patella morphology J:38423
abnormal phalanx morphology J:38423
abnormal tarsal bone morphology J:17582, J:38423
brachypodia J:17582
decreased length of long bones J:17582
fused carpal bones J:38423
fused phalanges J:17582
short metacarpal bones J:17582
short metatarsal bones J:17582
Gdf5bp-4J/Gdf5bp-4J
B6.Cg-Gdf5bp-4J/GrsrJ 		abnormal digit development J:190887
abnormal limb bone morphology J:190887
abnormal limb development J:190887
abnormal limb long bone morphology J:190887
abnormal phalanx morphology J:190887
brachyphalangia J:190887
disproportionate dwarf J:190887
fused phalanges J:190887
reduced male fertility J:190887
short metacarpal bones J:190887
short metatarsal bones J:190887
Gdf5Bp-5J/Gdf5+
C57BL/6J-Gdf5Bp-5J/GrsrJ 		abnormal limb morphology J:200816
brachydactyly J:200816
brachypodia J:200816
disproportionate dwarf J:200816
micromelia J:200816
Gdf5bp-6J/Gdf5bp-6J
DBA/2J-Gdf5bp-6J/GrsrJ 		brachydactyly J:226157
brachypodia J:226157
micromelia J:226157
Gdf5bp-H/Gdf5bp-H
involves: PCT 		abnormal cartilage development J:172114
abnormal endochondral bone ossification J:172114
abnormal femur morphology J:172114
abnormal fibula morphology J:172114
abnormal limb morphology J:172114
abnormal tibia morphology J:172114
short femur J:172114
short fibula J:172114
short tibia J:172114
Gdf5bp-H/Gdf5bp-H
involves: PCT stock * Swiss albino 		abnormal cartilage development J:166507
abnormal long bone epiphyseal plate morphology J:166507
delayed endochondral bone ossification J:166507
Gdf5bp-J/Gdf5+
A/J-Gdf5bp-J/J 		abnormal phalanx morphology J:59282
delayed bone ossification J:59282
Gdf5bp-J/Gdf5bp-J
A/J-Gdf5bp-J/J 		abnormal carpal bone morphology J:17582
abnormal digit development J:17582
abnormal digit morphology J:17582
abnormal limb bone morphology J:59288
abnormal limb development J:59288
abnormal limb mesenchyme morphology J:17582
abnormal phalanx morphology J:59288
abnormal tarsal bone morphology J:17582
brachyphalangia J:59282
brachypodia J:17582
decreased length of long bones J:17582
fused phalanges J:17582, J:59282
joint dislocation J:59282
short metacarpal bones J:17582, J:59282
short metatarsal bones J:17582, J:59282
Gdf5bp/Gdf5bp
Swiss albino stock 		abnormal limb bone morphology J:19596
abnormal long bone morphology J:19596
abnormal metacarpal bone morphology J:19596
abnormal metatarsal bone morphology J:19596
abnormal phalanx morphology J:19596
brachyphalangia J:19596
brachypodia J:19596
decreased length of long bones J:19596
disproportionate dwarf J:19596
short femur J:19596
short humerus J:19596
short tibia J:19596
short ulna J:19596
Gdf5brp/Gdf5brp
involves: NC 		abnormal autopod morphology J:124813
abnormal limb development J:31930
abnormal phalanx morphology J:124813
brachyphalangia J:124813
brachypodia J:31930
decreased birth weight J:31930
decreased body weight J:31930, J:124813
decreased length of long bones J:31930
decreased litter size J:124813
short femur J:31930
short fibula J:31930
short humerus J:31930
short limbs J:31930
short radius J:31930
short tibia J:31930
short ulna J:31930
Gdf5em1(IMPC)Bay/Gdf5em1(IMPC)Bay
C57BL/6N-Gdf5em1(IMPC)Bay/BayMmucd 		abnormal bone structure J:211773
decreased grip strength J:211773
Gdf5em1(IMPC)H/Gdf5em1(IMPC)H
C57BL/6NTac-Gdf5em1(IMPC)H/H 		abnormal autopod morphology J:211773
abnormal bone structure J:211773
abnormal digit morphology J:211773
abnormal forelimb morphology J:211773
abnormal gait J:211773
abnormal hindlimb morphology J:211773
decreased exploration in new environment J:211773
decreased locomotor activity J:211773
decreased lymphocyte cell number J:211773
decreased vertical activity J:211773
increased bone mineral density J:211773
limb grasping J:211773
Gdf5png/Gdf5png
C57BL/6Apb-Gdf5png/AnuApb 		decreased length of long bones J:104190
Gdf5Rgsc451/Gdf5+
C57BL/6JJcl-Gdf5Rgsc451 		abnormal cartilage morphology J:125122
abnormal phalanx morphology J:125122
brachypodia J:125122
fused joints J:125122
Gdf5Rgsc451/Gdf5Rgsc451
C57BL/6JJcl-Gdf5Rgsc451 		abnormal articular cartilage morphology J:125122
abnormal long bone epiphyseal plate morphology J:125122
abnormal long bone epiphysis morphology J:125122
abnormal phalanx morphology J:125122
decreased chondrocyte number J:125122
decreased length of long bones J:125122
fused joints J:125122
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory