Gdf5 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gdf5
growth differentiation factor 5
MGI:95688

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bmpr1b^{Tg(ACTB-FLP)4917Dym}/Bmpr1b^{Tg(ACTB-FLP)4917Dym} Gdf5^bp-J/Gdf5^bp-J involves: A/J * C57BL/6 * SJL	abnormal cartilage development	J:59288
	abnormal digit morphology	J:59288
	abnormal metacarpal bone morphology	J:59288
	abnormal metatarsal bone morphology	J:59288
Bmpr1b^tm1Kml/Bmpr1b⁺ Gdf5^bp-J/Gdf5⁺ involves: 129S/SvEv * A/J * C57BL/6J	abnormal phalanx morphology	J:59282
	delayed bone ossification	J:59282
Bmpr1b^tm1Kml/Bmpr1b^tm1Kml Gdf5^bp-J/Gdf5^bp-J involves: 129S/SvEv * A/J * C57BL/6J	abnormal limb morphology	J:59282
	fused metacarpal bones	J:59282
	fused metatarsal bones	J:59282
	short metacarpal bones	J:59282
Gdf5^bp-J/Gdf5^bp-J Gdf6^tm1Kng/Gdf6^tm1Kng involves: 129S1/Sv * 129X1/SvJ * A/J * C57BL/6J	abnormal carpal bone morphology	J:83132
	abnormal metatarsal bone morphology	J:83132
	abnormal phalanx morphology	J:83132
	abnormal vertebral articular process morphology	J:83132
	abnormal vertebral spinous process morphology	J:83132
	absent talus	J:83132
	bowed radius	J:83132
	delayed bone ossification	J:83132
	fused joints	J:83132
	premature death	J:83132
	scoliosis	J:83132
	short ulna	J:83132

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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